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AB167935

Recombinant Human SCY1 like 3 protein

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Recombinant Human SCY1 like 3 protein is a Human Full Length protein, in the 2 to 688 aa range, expressed in Baculovirus infected Sf9 cells, with >85%, suitable for SDS-PAGE, WB.

View Alternative Names

PACE1, SCYL3, Protein-associating with the carboxyl-terminal domain of ezrin, Ezrin-binding protein PACE-1, SCY1-like protein 3

1 Images
SDS-PAGE - Recombinant Human SCY1 like 3 protein (AB167935)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SCY1 like 3 protein (AB167935)

SDS-PAGE analysis of ab167935.

Key facts

Purity

>85% Densitometry

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

SDS-PAGE, WB

applications

Biologically active

No

Accession

Q8IZE3

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.79% Tris HCl, 0.31% Glutathione, 0.29% Sodium chloride, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"GSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLLSHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKIFKRTAPSFTKNTDLSLEGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPENQTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSAEQKPIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFTIQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAEITEGEAEGWEEEGELNWEDNNW","proteinLength":"Full Length","predictedMolecularWeight":"110 kDa","actualMolecularWeight":null,"aminoAcidEnd":688,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":"Baculovirus infected Sf9 cells","accessionNumber":"Q8IZE3","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SCY1 like 3 (SCYL3) also known as TSARG2 or Nbla10080 acts as a pseudo kinase with a molecular mass of about 89 kDa. This protein mostly localizes in the cytoplasm where it plays a role in cellular processes. SCYL3 is widely expressed in various tissues with noticeable presence in the brain heart and kidney.
Biological function summary

SCYL3 functions as a structural regulator rather than facilitating enzymatic activity due to its lack of kinase activity. It involves in intracellular trafficking processes. Part of a protein complex observed in the intracellular Golgi apparatus SCYL3 facilitates the transport of molecules and might influence membrane dynamics.

Pathways

SCYL3 interacts within the vesicular transport pathway and is involved in protein trafficking. It associates with other proteins such as clathrin and the Golgi-associated proteins influencing how proteins are packaged and moved through the Golgi. SCYL3’s interaction in these pathways highlights its role in maintaining protein transport efficiency and cellular organization.

SCYL3 has potential links to neurodegenerative diseases including Alzheimer’s disease. Research indicates that it might interact with tau protein important in Alzheimer’s pathology. Additionally SCYL3's dysfunction or aberrant expression could be related to cancer development possibly via alterations in protein trafficking systems therefore connecting it to proteins like p53 that influence cell cycle and apoptosis.
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Specifications

Form

Liquid

Additional notes

Affinity purified.

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General info

Function

May play a role in regulating cell adhesion/migration complexes in migrating cells.

Sequence similarities

Belongs to the protein kinase superfamily.

Post-translational modifications

May be myristoylated; myristoylation may target it to Golgi compartment.. Phosphorylated.

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Product protocols

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Target data

May play a role in regulating cell adhesion/migration complexes in migrating cells.
See full target information SCYL3
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