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AB166189

Recombinant Human SEC14L4 protein (GST tag N-Terminus)

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Recombinant Human SEC14L4 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 352 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

TAP3, SEC14L4, SEC14-like protein 4, Tocopherol-associated protein 3

1 Images
SDS-PAGE - Recombinant Human SEC14L4 protein (GST tag N-Terminus) (AB166189)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SEC14L4 protein (GST tag N-Terminus) (AB166189)

ab166189 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q9UDX3

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MLRRHMEFRKQQDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYTVEVLLPDKASEETLQSLKAMRPSPTQ","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":352,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9UDX3","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SEC14L4 also known as SEC14-like protein 4 is a protein involved in lipid metabolism and intracellular transport. It is a member of the SEC14 superfamily and functions as a lipid and phospholipid transfer protein. SEC14L4 has a molecular mass of approximately 63 kDa. The protein is expressed in several tissues including liver and brain with expression levels that vary depending on the tissue type.
Biological function summary

SEC14-like function is associated with the regulation of lipid homeostasis and intracellular trafficking. It operates within the endoplasmic reticulum and Golgi apparatus participating in lipid transfer processes important for maintaining cellular lipid balance. SEC14L4 does not typically form part of larger protein complexes but interacts with membrane lipids to perform its role in the cell.

Pathways

SEC14L4 is involved in the phospholipid metabolic and vesicle-mediated transport pathways. It is closely associated with the function of proteins such as phosphatidylinositol 4-kinase and its role in maintaining the phosphoinositide pool which is critical for vesicular trafficking in the cell. These pathways are essential for cellular homeostasis and organelle function.

SEC14L4 has been implicated in neurological conditions such as potential connections to Alzheimer's disease where lipid transport imbalance appears to play a role. The protein also shows relevance in metabolic disorders such as fatty liver disease linked to disruptions in lipid homeostasis. SEC14L4 may interact with proteins involved in these conditions such as tau protein in Alzheimer's disease indicating a possible pathway through which its dysregulation could impact disease progression.
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Specifications

Form

Liquid

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General info

Function

Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.

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Product protocols

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Target data

Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
See full target information SEC14L4
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