Recombinant Human Secretogranin 3 protein (His tag N-Terminus)
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Recombinant Human Secretogranin 3 protein (His tag N-Terminus) is a Human Full Length protein, in the 20 to 468 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
View Alternative Names
UNQ2502/PRO5990, SCG3, Secretogranin-3, Secretogranin III, SgIII
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Secretogranin 3 protein (His tag N-Terminus) (AB167866)
15% SDS-PAGE analysis of 3µg ab167866.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Secretogranin 3 helps regulate hormone secretion processes. It often works alongside other granin proteins within vesicles in neuroendocrine systems. Together with proteins like chromogranin A and chromogranin B it aids in sorting and packing peptide hormones and neuropeptides critical for cell communication. This coordination ensures that necessary signaling molecules are released appropriately to maintain normal physiological functions.
Pathways
Secretogranin 3 operates within the secretory and neuroendocrine regulation pathways. It interacts with proteins involved in vesicle formation and transport such as synaptotagmins and syntaxins. These pathways are important in processes such as neurotransmitter release and hormone secretion. The interplay between Secretogranin 3 and these proteins supports the controlled secretion of hormones which is important for cell signaling and homeostasis.
Specifications
Form
Liquid
Additional notes
ab167866 was purified using conventional chromatography techniques.
General info
Function
Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed : 19357184). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed : 29154827).
Post-translational modifications
O-glycosylated.
Target data
Product promise
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