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Recombinant Human SEI-1 protein is a Human Full Length protein, in the 1 to 236 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
Alternative names=SERTA domain-containing protein 1, CDK4-binding protein p34SEI1, Transcriptional regulator interacting with the PHD-bromodomain 1, SEI-1, p34(SEI-1), TRIP-Br1, TRIPBR1, SEI1, SERTAD1
- Purity
>85% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S H M L S K G L K R K R E E E E E K E P L A V D S W W L D P G H T A V A Q A P P A V A S S S L F D L S V L K L H H S L Q Q S E P D L R H L V L V V N T L R R I Q A S M A P A A A L P P V P S P P A A P S V A D N L L A S S D A A L S A S M A S L L E D L S H I E G L S Q A P Q P L A D E G P P G R S I G G A A P S L G A L D L L G P A T G C L L D D G L E G L F E D I D T S M Y D N E L W A P A S E G L K P G P E D G P G K E E A P E L D E A E L D Y L M D V L V G T Q A L E R P P G P G R
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Images
Target data
Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
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Recombinant Human SEI-1 protein is a Human Full Length protein, in the 1 to 236 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE, MS.
Alternative names=SERTA domain-containing protein 1, CDK4-binding protein p34SEI1, Transcriptional regulator interacting with the PHD-bromodomain 1, SEI-1, p34(SEI-1), TRIP-Br1, TRIPBR1, SEI1, SERTAD1
Key facts
- Purity
>85% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Predicted molecular weight
27.3 kDa
- Amino acids
1 to 236
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S H M L S K G L K R K R E E E E E K E P L A V D S W W L D P G H T A V A Q A P P A V A S S S L F D L S V L K L H H S L Q Q S E P D L R H L V L V V N T L R R I Q A S M A P A A A L P P V P S P P A A P S V A D N L L A S S D A A L S A S M A S L L E D L S H I E G L S Q A P Q P L A D E G P P G R S I G G A A P S L G A L D L L G P A T G C L L D D G L E G L F E D I D T S M Y D N E L W A P A S E G L K P G P E D G P G K E E A P E L D E A E L D Y L M D V L V G T Q A L E R P P G P G R
- Accession
- Q9UHV2-1
- Protein length
Full Length
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Specifications
- Form
Liquid
- Additional notes
ab130022 was purified using conventional chromatography.
General info
- Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
- Post-translational modifications
Polyubiquitinated, which promotes proteasomal degradation.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
Previously labelled as Sertad1.
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