Skip to main content

Recombinant human SET7 protein is a Human Full Length protein, in the 1 to 366 aa range, expressed in Baculovirus infected Sf9, with >95% purity and suitable for SDS-PAGE, WB, FuncS.

This product has no reviews yet! Submit a review
Purity

>95% SDS-PAGE

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

SDS-PAGE, WB, FuncS

Biologically active

Yes

Sequence

M D S D D E M V E E A V E G H L D D D G L P H G F C T V T Y S S T D R F E G N F V H G E K N G R G K F F F F D G S T L E G Y Y V D D A L Q G Q G V Y T Y E D G G V L Q G T Y V D G E L N G P A Q E Y D T D G R L I F K G Q Y K D N I R H G V C W I Y Y P D G G S L V G E V N E D G E M T G E K I A Y V Y P D E R T A L Y G K F I D G E M I E G K L A T L M S T E E G R P H F E L M P G N S V Y H F D K S T S S C I S T N A L L P D P Y E S E R V Y V A E S L I S S A G E G L F S K V A V G P N T V M S F Y N G V R I T H Q E V D S R D W A L N G N T L S L D E E T V I D V P E P Y N H V S K Y C A S L G H K A N H S F T P N C I Y D M F V H P R F G P I K C I R T L R A V E A D E E L T V A Y G Y D H S P P G K S G P E A P E W Y Q V E L K A F Q A T Q Q K

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Shipping To:
United States

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Application
WB
Reactivity
Reacts
Dilution info
-
Notes

-

Application
FuncS
Reactivity
Reacts
Dilution info
-
Notes

-

Images

Target data

Recommended products

  1. Loading...
  2. Loading...
  3. Loading...
  4. Loading...

Recombinant human SET7 protein is a Human Full Length protein, in the 1 to 366 aa range, expressed in Baculovirus infected Sf9, with >95% purity and suitable for SDS-PAGE, WB, FuncS.

Key facts

Purity

>95% SDS-PAGE

Expression system

Baculovirus infected Sf9 cells

Applications

SDS-PAGE, WB, FuncS

Biological activity

The specific activity of ab167960 was determined to be 40 nmol/min/mg as per activity assay protocol.

Predicted molecular weight

75 kDa

Amino acids

1 to 366

Sequence

M D S D D E M V E E A V E G H L D D D G L P H G F C T V T Y S S T D R F E G N F V H G E K N G R G K F F F F D G S T L E G Y Y V D D A L Q G Q G V Y T Y E D G G V L Q G T Y V D G E L N G P A Q E Y D T D G R L I F K G Q Y K D N I R H G V C W I Y Y P D G G S L V G E V N E D G E M T G E K I A Y V Y P D E R T A L Y G K F I D G E M I E G K L A T L M S T E E G R P H F E L M P G N S V Y H F D K S T S S C I S T N A L L P D P Y E S E R V Y V A E S L I S S A G E G L F S K V A V G P N T V M S F Y N G V R I T H Q E V D S R D W A L N G N T L S L D E E T V I D V P E P Y N H V S K Y C A S L G H K A N H S F T P N C I Y D M F V H P R F G P I K C I R T L R A V E A D E E L T V A Y G Y D H S P P G K S G P E A P E W Y Q V E L K A F Q A T Q Q K

Accession
Q8WTS6-1
Protein length

Full Length

Animal free

No

Nature

Recombinant

Species

Human

Concentration
Loading...
Storage buffer

pH: 7.5
Constituents: 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.79% Tris HCl, 0.31% Glutathione, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

Specifications

Form

Liquid

Additional notes

Assessed by densitometry. Affinity purified.

General info

Function

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Sequence similarities

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.

Subcellular localisation

Nucleus

Storage

Shipped at conditions

Dry Ice

Appropriate long-term storage conditions

-80°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

There was a problem

We can’t download that datasheet. Please try again. If you need help, contact our Customer Services team at technical@abcam.com