JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB276605

Recombinant Human SEZ6L2 protein (His tag)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human SEZ6L2 protein (His tag) is a Human Fragment protein, in the 1 to 736 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

PSK, UNQ1903/PRO4349, SEZ6L2, Seizure 6-like protein 2

1 Images
SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)

SDS-PAGE analysis of ab276605.

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q6UXD5

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

style
left-column

Complementary Products

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

  • 0
  • 0
Proteins & Peptides

AB164531

Recombinant Human TRAF7 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human TRAF7 protein (GST tag N-Terminus) (AB164531)

  • 0
  • 0
Proteins & Peptides

AB162150

Recombinant Human TMEM97 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human TMEM97 protein (GST tag N-Terminus) (AB162150)

  • 0
  • 0
Proteins & Peptides

AB162265

Recombinant Human Epsin 1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Epsin 1 protein (GST tag N-Terminus) (AB162265)

  • 0
  • 0
Proteins & Peptides

AB162041

Recombinant Human STEAP1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human STEAP1 protein (GST tag N-Terminus) (AB162041)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"linker":null,"sequence":"MGTPRAQHPPPPQLLFLILLSCPWIQGLPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGPEGGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS","proteinLength":"Fragment","predictedMolecularWeight":"77.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":736,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6UXD5","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
style
left-column

Properties and storage information

Form
Lyophilized
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SEZ6L2 also known as Seizure 6-like protein 2 is a transmembrane protein with an approximate mass of 100 kDa. This protein contains several domains including CUB and Sushi/SCR/CCP domains which suggest roles in cell signal recognition and interaction. SEZ6L2 expresses mainly in the brain with a concentration in regions such as the cerebral cortex and hippocampus implicating it within processes critical to neurological development and function.
Biological function summary

SEZ6L2 has important roles in synaptic transmission and plasticity. It is part of a larger complex that influences the development and maintenance of synapses. Current research suggests that SEZ6L2 affects the signaling pathways in neurons and may involve the modulation of synaptic strength impacting cognitive functions such as learning and memory.

Pathways

SEZ6L2 is involved in the regulation of synaptic signaling pathways. It interacts significantly with proteins in the cAMP signaling pathway which is important for translating extracellular signals into cellular responses and neurotrophic pathway which involves proteins like BDNF. These pathways are essential for cellular survival differentiation and plasticity in neural cells further linking SEZ6L2 to neurological processes.

SEZ6L2 has associations with several neurological conditions including epilepsy and autism spectrum disorders. In epilepsy SEZ6L2 interacts with other seizure-related proteins that affect neuronal excitability and network stability. For autism spectrum disorders changes in SEZ6L2 expression or function likely alter synaptic connectivity and signal transmission influencing behavioral and cognitive symptoms associated with this disorder.
style
left-column

General info

Function

May contribute to specialized endoplasmic reticulum functions in neurons.

Sequence similarities

Belongs to the SEZ6 family.

Post-translational modifications

O-glycosylated with core 1 or possibly core 8 glycans.

style
left-column

Product protocols

style
left-column

Target data

May contribute to specialized endoplasmic reticulum functions in neurons.
See full target information SEZ6L2
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com