Recombinant Human Siglec 9 Protein (Fc-tag)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human Siglec 9 Protein (Fc-tag) is a Human Fragment protein, in the 18 to 348 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for HPLC, SDS-PAGE, Mass Spec.
View Alternative Names
CD329, UNQ668/PRO1302, SIGLEC9, Sialic acid-binding Ig-like lectin 9, Siglec-9, CDw329, Protein FOAP-9
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Human Siglec 9 Protein (Fc-tag) (AB307794)
Mass determination by ESI-TOF. Predicted MW is 61975.68 Da (+/- 10 Da by ESI-TOF). Observed MW is 61844.90 Da.
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Siglec 9 Protein (Fc-tag) (AB307794)
SDS-PAGE analysis of ab307794
- HPLC
Supplier Data
HPLC - Recombinant Human Siglec 9 Protein (Fc-tag) (AB307794)
HPLC analysis of ab307794
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein is involved in immune regulation helping to modulate immune responses and maintain self-tolerance to prevent autoimmunity. SIGLEC9 can recognize sialylated ligands on cell surfaces and interact with them to down-modulate immune cell activation. This protein is not known to be part of a specific complex but interacts directly with ligands on other cells influencing cellular communication and immune cell signaling within the microenvironment.
Pathways
SIGLEC9 participates primarily in the immune response pathway and interacts with pathways related to inflammation regulation. It works alongside proteins such as SIRPα which also plays a role in signaling pathways that result in immune cell inhibition. This coordination is critical to suppressing overactive immune responses and ensuring damage does not occur to host tissues during inflammation.
Specifications
Form
Lyophilized
Additional notes
SDS-PAGE >= 95%
General info
Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Sequence similarities
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Target data
Complementary Products
Primary Antibodies
AB9485
Anti-GAPDH antibody - Loading Control
BOND RX™ Validated|Lab Essentials
- 5
- 88
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com