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Recombinant Human SIGLEC6 protein (Fc Chimera) is a Human Fragment protein, in the 16 to 320 aa range, expressed in HEK 293, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Alternative names=Sialic acid-binding Ig-like lectin 6, Siglec-6, CD33 antigen-like 1, CDw327, Obesity-binding protein 1, OB-BP1, SIGLEC6, CD33L, CD33L1, OBBP1
- Purity
>90% SDS-PAGE
- Endotoxin level
< 1 EU/µg
- Expression system
HEK 293 cells
- Tags
Fc tag C-Terminus
- Applications
SDS-PAGE
- Biologically active
No
- Sequence
L L P L L W A G A L A Q E R R F Q L E G P E S L T V Q E G L C V L V P C R L P T T L P A S Y Y G Y G Y W F L E G A D V P V A T N D P D E E V Q E E T R G R F H L L W D P R R K N C S L S I R D A R R R D N A A Y F F R L K S K W M K Y G Y T S S K L S V R V M A L T H R P N I S I P G T L E S G H P S N L T C S V P W V C E Q G T P P I F S W M S A A P T S L G P R T T Q S S V L T I T P R P Q D H S T N L T C Q V T F P G A G V T M E R T I Q L N V S Y A P Q K V A I S I F Q G N S A A F K I L Q N T S S L P V L E G Q A L R L L C D A D G N P P A H L S W F Q G F P A L N A T P I S N T G V L E L P Q V G S A E E G D F T C R
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant Human SIGLEC6 protein (Fc Chimera) is a Human Fragment protein, in the 16 to 320 aa range, expressed in HEK 293, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Alternative names=Sialic acid-binding Ig-like lectin 6, Siglec-6, CD33 antigen-like 1, CDw327, Obesity-binding protein 1, OB-BP1, SIGLEC6, CD33L, CD33L1, OBBP1
Key facts
- Purity
>90% SDS-PAGE
- Endotoxin level
< 1 EU/µg
- Expression system
HEK 293 cells
- Tags
Fc tag C-Terminus
- Applications
SDS-PAGE
- Biologically active
No
- Predicted molecular weight
60.3 kDa
- Amino acids
16 to 320
- Sequence
L L P L L W A G A L A Q E R R F Q L E G P E S L T V Q E G L C V L V P C R L P T T L P A S Y Y G Y G Y W F L E G A D V P V A T N D P D E E V Q E E T R G R F H L L W D P R R K N C S L S I R D A R R R D N A A Y F F R L K S K W M K Y G Y T S S K L S V R V M A L T H R P N I S I P G T L E S G H P S N L T C S V P W V C E Q G T P P I F S W M S A A P T S L G P R T T Q S S V L T I T P R P Q D H S T N L T C Q V T F P G A G V T M E R T I Q L N V S Y A P Q K V A I S I F Q G N S A A F K I L Q N T S S L P V L E G Q A L R L L C D A D G N P P A H L S W F Q G F P A L N A T P I S N T G V L E L P Q V G S A E E G D F T C R
- Accession
- O43699-1
- Protein length
Fragment
- Animal free
No
- Nature
Recombinant
- Species
Human
- Reconstitution
Reconstitute with sterile deionized water to a concentration of 200 µg/ml.
- Concentration
- Storage buffer
pH: 7.4
Constituents: 5% Trehalose, 0.75% Glycine, 0.6% Tris
Specifications
- Form
Lyophilized
General info
- Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
- Sequence similarities
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Storage information
Avoid freeze / thaw cycle
Notes
DTT-reduced SIGLEC6 protein migrates as 80-90 kDa and non-reduced protein migrates as 160-180 kDa.
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