Recombinant Human SLC27A4 / FATP4 protein is a Human Full Length protein, in the 1 to 237 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Images
Key facts
- Expression system
- Wheat germ
- Tags
- Tag free
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
Amino acid sequence
M P L T L S T L L Q P G R I W T G R R A A E P T P G H N A A W S L S G G G A A V L Q A G A E T A L D P G G I L P V V P L L G I W R L A L H P G L H Q D H Q A Y L T G D V L V M D E L G Y L Y F R D R T G D T F R W K G E N V S T T E V E G T L S R L L D M A D V A V Y G V E V P G T E G R A G M A A V A S P T G N C D L E R F A Q V L E K E L P L Y A R P I F L R L L P E L H K T G T Y K F Q K T E L R K E G F D P A I V K D P L F Y L D A Q K G R Y V P L D Q E A Y S R I Q A G E E K L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed:10518211, PubMed:12556534, PubMed:20448275, PubMed:21395585, PubMed:22022213). Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed:20448275). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:22022213, PubMed:24269233). Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed:21395585). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
Alternative names
ACSVL4, FATP4, SLC27A4, Long-chain fatty acid transport protein 4, FATP-4, Fatty acid transport protein 4, Arachidonate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 4, Very long-chain acyl-CoA synthetase 4
Recommended products
Recombinant Human SLC27A4 / FATP4 protein is a Human Full Length protein, in the 1 to 237 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Key facts
- Expression system
- Wheat germ
- Tags
- Tag free
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
- Accession
- Q6P1M0-2
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
- M P L T L S T L L Q P G R I W T G R R A A E P T P G H N A A W S L S G G G A A V L Q A G A E T A L D P G G I L P V V P L L G I W R L A L H P G L H Q D H Q A Y L T G D V L V M D E L G Y L Y F R D R T G D T F R W K G E N V S T T E V E G T L S R L L D M A D V A V Y G V E V P G T E G R A G M A A V A S P T G N C D L E R F A Q V L E K E L P L Y A R P I F L R L L P E L H K T G T Y K F Q K T E L R K E G F D P A I V K D P L F Y L D A Q K G R Y V P L D Q E A Y S R I Q A G E E K L
- Accession
- Q6P1M0
- Protein length
- Full Length
- Predicted molecular weight
- 51.81 kDa
- Amino acids
- 1 to 237
- Nature
- Recombinant
Specifications
- Form
- Liquid
General info
- Function
Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed:10518211, PubMed:12556534, PubMed:20448275, PubMed:21395585, PubMed:22022213). Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed:20448275). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:22022213, PubMed:24269233). Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed:21395585). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
- Sequence similarities
Belongs to the ATP-dependent AMP-binding enzyme family.
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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1 product image
SDS-PAGE - Recombinant Human SLC27A4 / FATP4 protein (ab132824)
12.5% SDS-PAGE analysis of ab132824 stained with Coomassie Blue.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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