Recombinant Human SLC27A4 / FATP4 protein (GST tag N-Terminus)
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Recombinant Human SLC27A4 / FATP4 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 237 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.
View Alternative Names
ACSVL4, FATP4, SLC27A4, Long-chain fatty acid transport protein 4, FATP-4, Fatty acid transport protein 4, Arachidonate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 4, Very long-chain acyl-CoA synthetase 4
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human SLC27A4 / FATP4 protein (GST tag N-Terminus) (AB132824)
12.5% SDS-PAGE analysis of ab132824 stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed : 10518211, PubMed : 12556534, PubMed : 20448275, PubMed : 21395585, PubMed : 22022213). Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed : 20448275). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed : 22022213, PubMed : 24269233). Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity). Probably involved in fatty acid transport across the blood barrier (PubMed : 21395585). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
Sequence similarities
Belongs to the ATP-dependent AMP-binding enzyme family.
Target data
Product promise
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