Recombinant Human SNRPA1 protein
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human SNRPA1 protein is a Human Full Length protein, in the 1 to 255 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
U2 small nuclear ribonucleoprotein A', U2 snRNP A', SNRPA1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human SNRPA1 protein (AB116200)
15% SDS-PAGE analysis of 3 µg ab116200.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The small nuclear ribonucleoprotein-associated protein A1 plays an important role in the splicing of pre-mRNA. It is part of the U1 snRNP complex which is important for the recognition and selection of 5' splice sites in pre-mRNA transcripts. This protein aids in the assembly of the spliceosome the large ribonucleoprotein complex responsible for catalyzing the excision of introns. SNRPA1 ensures the fidelity and regulation of mRNA maturation affecting gene expression levels.
Pathways
The involvement of SNRPA1 in the spliceosome cycle places it within the post-transcriptional modification and gene expression regulation pathways. It is intricately related to other spliceosomal components like U2 snRNP which is essential for the branch point recognition in the splicing process. Together with proteins such as SF3B1 SNRPA1 plays a role in the coordination and timing of splice site recognition and catalysis during the splicing pathway.
Specifications
Form
Liquid
Additional notes
ab116200 was purified using conventional chromatography.
General info
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed : 11991638, PubMed : 27035939, PubMed : 28076346, PubMed : 28502770, PubMed : 28781166, PubMed : 32494006). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed : 27035939, PubMed : 32494006, PubMed : 9716128).
Sequence similarities
Belongs to the U2 small nuclear ribonucleoprotein A family.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com