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AB84639

Recombinant Human SOD2/MnSOD protein

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(1 Publication)

Recombinant Human SOD2/MnSOD protein is a Human Full Length protein, in the 1 to 222 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, WB.

View Alternative Names

SOD2

1 Images
SDS-PAGE - Recombinant Human SOD2/MnSOD protein (AB84639)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SOD2/MnSOD protein (AB84639)

Key facts

Purity

>90% Densitometry

Expression system

Escherichia coli

Tags

GST tag N-Terminus

Applications

WB, SDS-PAGE

applications

Biologically active

No

Accession

P04179

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.00174% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":222,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"P04179","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Post-translational modifications

Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity.. Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity).. Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability.

Subcellular localisation

Mitochondrion matrix

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Product protocols

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Target data

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
See full target information Superoxide dismutase [Mn], mitochondrial
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 25:2605-2616.e7 PubMed30485823

2018

Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance.

Applications

Unspecified application

Species

Unspecified reactive species

Sara Zemanovic,Maxim V Ivanov,Lena V Ivanova,Amogh Bhatnagar,Teresa Michalkiewicz,Ru-Jeng Teng,Suresh Kumar,Rajendra Rathore,Kirkwood A Pritchard,Girija G Konduri,Adeleye J Afolayan
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Product promise

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For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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