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AB134856

Recombinant Human SOX13 protein

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Recombinant Human SOX13 protein is a Human Full Length protein, in the 2 to 622 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

View Alternative Names

Transcription factor SOX-13, Islet cell antigen 12, SRY (Sex determining region Y)-box 13, Type 1 diabetes autoantigen ICA12, SOX13

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9UN79

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 3.4% DL-Arginine, 0.32% Tris HCl, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.02% EDTA

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Complementary Products

Primary Antibodies

AB96776

Anti-SOX13 antibody

Immunocytochemistry/ Immunofluorescence - Anti-SOX13 antibody (AB96776)

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Primary Antibodies

AB302891

Anti-PKC theta/PRKCQ antibody [27/PKC theta]

20ul selling size|Recombinant|Trial Size

Western blot - Anti-PKC theta/PRKCQ antibody [27/PKC theta] (AB302891)

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Primary Antibodies

AB122124

Anti-SLCO4A1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SLCO4A1 antibody (AB122124)

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Proteins & Peptides

AB167848

Recombinant Human BSND protein

SDS-PAGE - Recombinant Human BSND protein (AB167848)

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  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" } } }
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Sequence info

[{"sequence":"29aa_Tag_ SMRSPIS AQLALDGVGT MVNCTIKSEE KKEPCHEAPQ GSATAAEPQP GDPARASQDS ADPQAPAQGN FRGSWDCSSP EGNGSPEPKR PGVSEAASGS QEKLDFNRNL KEVVPAIEKL LSSDWKERFL GRNSMEAKDV KGTQESLAEK ELQLLVMIHQ LSTLRDQLLT AHSEQKNMAA MLFEKQQQQM ELARQQQEQI AKQQQQLIQQ QHKINLLQQQ IQQVNMPYVM IPAFPPSHQP LPVTPDSQLA LPIQPIPCKP VEYPLQLLHS PPAPVVKRPG AMATHHPLQE PSQPLNLTAK PKAPELPNTS SSPSLKMSSC VPRPPSHGGP TRDLQSSPPS LPLGFLGEGD AVTKAIQDAR QLLHSHSGAL DGSPNTPFRK DLISLDSSPA KERLEDGCVH PLEEAMLSCD MDGSRHFPES RNSSHIKRPM NAFMVWAKDE RRKILQAFPD MHNSSISKIL GSRWKSMTNQ EKQPYYEEQA RLSRQHLEKY PDYKYKPRPK RTCIVEGKRL RVGEYKALMR TRRQDARQSY VIPPQAGQVQ MSSSDVLYPR AAGMPLAQPL VEHYVPRSLD PNMPVIVNTC SLREEGEGTD DRHSVADGEM YRYSEDEDSE GEEKSDGELV VLTDLEESGG GGSPGRRRRR RRRRRR","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":622,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9UN79","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab134856 was expressed in E. coli as inclusion bodies, refolded using the unique “temperature shift inclusion body refolding” technology, chromatographically purified and sterile filtered.

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General info

Function

Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed : 10871192). Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity). Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity). Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (By similarity). Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (By similarity). Promotes brown adipocyte differentiation (By similarity). Inhibitor of WNT signaling (PubMed : 20028982).

Subcellular localisation

Nucleus

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Product protocols

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Target data

Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed : 10871192). Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity). Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity). Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (By similarity). Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (By similarity). Promotes brown adipocyte differentiation (By similarity). Inhibitor of WNT signaling (PubMed : 20028982).
See full target information Transcription factor SOX-13
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Product promise

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