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AB168077

Recombinant Human SPAG7 protein

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Recombinant Human SPAG7 protein is a Human Full Length protein, in the 1 to 227 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Sperm-associated antigen 7, SPAG7

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SDS-PAGE - Recombinant Human SPAG7 protein (AB168077)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human SPAG7 protein (AB168077)

3 µg ab168077 on 15% SDS-PAGE

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

O75391

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 30% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPPTS","proteinLength":"Full Length","predictedMolecularWeight":"28 kDa","actualMolecularWeight":null,"aminoAcidEnd":227,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O75391","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SPAG7 also known as Sperm Associated Antigen 7 is a protein with an approximate mass of 26 kilodaltons. It is mainly expressed in the testis with additional expression noted in other tissues at lower levels. Mechanically SPAG7 functions in the regulation of cellular processes associated with spermatogenesis playing a role in the assembly and reorganization of microtubule structures.
Biological function summary

SPAG7 enhances the development and function of sperm cells contributing significantly to male fertility. The protein participates in microtubule-related activities and likely interacts with other proteins to perform its roles effectively. Research suggests that SPAG7 does not form a complex on its own but it closely associates with other cellular components in sperm maturation.

Pathways

SPAG7 interacts with regulatory networks involved in cilia and flagella movement contributing to the sperm's motility. SPAG7 shows a relationship with proteins like dynein and kinesin which are important in microtubule dynamics and cellular transport processes. It plays a part in pathways such as the spermatogenesis pathway where it ensures proper function and motility of sperm cells through its interactions with other proteins.

SPAG7 has associations with male infertility which is often linked to defective spermatogenesis and sperm motility issues. Abnormal SPAG7 expression may disrupt cellular transport processes causing infertility. Although not directly implicated in diseases like cancer alterations in SPAG7 levels could potentially influence cancer-associated proteins through indirect pathways reflecting complex biological interactions.
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Specifications

Form

Liquid

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General info

Subcellular localisation

Nucleus

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Product protocols

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Target data

See full target information SPAG7
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Complementary Products

Primary Antibodies

AB181187

Anti-SPAG7 antibody [EPR13391]

RabMAb|Recombinant

Immunoprecipitation - Anti-SPAG7 antibody [EPR13391] (AB181187)

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Cell Lines & Lysates

AB258697

Human SPAG7 knockout HEK-293T cell lysate

Sanger Sequencing - Human SPAG7 knockout HEK-293T cell lysate (AB258697)

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Cell Lines & Lysates

AB266775

Human SPAG7 knockout HEK-293T cell line

Sanger Sequencing - Human SPAG7 knockout HEK-293T cell line (AB266775)

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Product promise

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