Recombinant Human Sterol carrier protein 2 is a Human Full Length protein, in the 1 to 143 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Images
Key facts
- Expression system
- Wheat germ
- Tags
- Tag free
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
Amino acid sequence
M G F P E A A S S F R T H Q I E A V P T S S A S D G F K A N L V F K E I E K K L E E E G E Q F V K K I G G I F A F K V K D G P G G K E A T W V V D V K N G K G S V L P N S D K K A D C T I T M A D S D F L A L M T G K M N P Q S A F F Q G K L K I T G N M G L A M K L Q N L Q L Q P G N A K L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes Recombinant protein. |
Target data
Function
Isoform SCPx. Plays a crucial role in the peroxisomal oxidation of branched-chain fatty acids (PubMed:10706581). Catalyzes the last step of the peroxisomal beta-oxidation of branched chain fatty acids and the side chain of the bile acid intermediates di- and trihydroxycoprostanic acids (DHCA and THCA) (PubMed:10706581). Also active with medium and long straight chain 3-oxoacyl-CoAs. Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol and transfers phosphatidylcholine and 7-dehydrocholesterol between membrances, in vitro (By similarity). Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs (By similarity). Isoform SCP2. Mediates the transfer of all common phospholipids, cholesterol and gangliosides from the endoplasmic reticulum to the plasma membrane. May play a role in regulating steroidogenesis (PubMed:17157249, PubMed:7642518, PubMed:8300590). Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol (By similarity). Also binds fatty acids and fatty acyl Coenzyme A (CoA) such as phytanoyl-CoA. Involved in the regulation phospholipid synthesis in endoplasmic reticulum enhancing the incorporation of exogenous fatty acid into glycerides. Seems to stimulate the rate-limiting step in phosphatidic acid formation mediated by GPAT3. Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs (By similarity).
Alternative names
Sterol carrier protein 2, SCP-2, Acetyl-CoA C-myristoyltransferase, Non-specific lipid-transfer protein, Propanoyl-CoA C-acyltransferase, SCP-2/3-oxoacyl-CoA thiolase, SCP-2/thiolase, SCP-chi, SCPX, Sterol carrier protein X, NSL-TP, SCP-X, SCP2
Recommended products
Recombinant Human Sterol carrier protein 2 is a Human Full Length protein, in the 1 to 143 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
Key facts
- Expression system
- Wheat germ
- Tags
- Tag free
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
- Accession
- P22307-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.3% Glutathione
Sequence info
Amino acid sequence
- M G F P E A A S S F R T H Q I E A V P T S S A S D G F K A N L V F K E I E K K L E E E G E Q F V K K I G G I F A F K V K D G P G G K E A T W V V D V K N G K G S V L P N S D K K A D C T I T M A D S D F L A L M T G K M N P Q S A F F Q G K L K I T G N M G L A M K L Q N L Q L Q P G N A K L
- Accession
- P22307
- Protein length
- Full Length
- Predicted molecular weight
- 41.84 kDa
- Amino acids
- 1 to 143
- Nature
- Recombinant
Specifications
- Form
- Liquid
General info
- Function
Isoform SCPx
- Sequence similarities
In the N-terminal section; belongs to the thiolase-like superfamily. Thiolase family.
- Post-translational modifications
Isoform SCP2
- Subcellular localisation
- Peroxisome, Mitochondrion
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human Sterol carrier protein 2 (ab117049)
12.5% SDS-PAGE showing ab117049 at approximately 41.84 kDa.
Stained with Coomassie Blue.
Downloads
Product protocols
- Visit the general protocols
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