Recombinant Human STK16 protein (His tag N-Terminus)
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Recombinant Human STK16 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 305 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
MPSK1, PKL12, TSF1, STK16, Serine/threonine-protein kinase 16, Myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, Tyrosine-protein kinase STK16, hPSK, MPSK, TSF-1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human STK16 protein (His tag N-Terminus) (AB126668)
15% SDS-PAGE analysis of 3 µg ab126668.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
STK16 influences various processes at the cellular level. It participates in vesicular trafficking and Golgi function ensuring proper sorting and delivery of proteins within cells. Although not typically seen as part of large complexes it interacts with several other proteins to exert its biological roles. The protein’s activity affects cell cycle progression and can influence cellular growth and motility.
Pathways
STK16 integrates into key regulatory networks such as the Golgi-associated vesicle budding pathway and cell signaling pathways. These pathways are important for maintaining cellular organization and communication. STK16’s interactions with proteins like COPII in vesicle trafficking and possibly components of the MAPK signaling cascade highlight its connectivity within cellular pathways and its regulatory potential.
Specifications
Form
Liquid
Additional notes
ab126668 is purified using conventional chromatography.
General info
Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Sequence similarities
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Post-translational modifications
Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198.. It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8.
Target data
Complementary Products
Product promise
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