JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB160470

Recombinant Human STOML1 protein (GST tag N-Terminus)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human STOML1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 398 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

SLP1, UNC24, MSTP019, STOML1, Stomatin-like protein 1, SLP-1, EPB72-like protein 1, Protein unc-24 homolog, Stomatin-related protein, STORP

1 Images
SDS-PAGE - Recombinant Human STOML1 protein (GST tag N-Terminus) (AB160470)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human STOML1 protein (GST tag N-Terminus) (AB160470)

ab160470 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q9UBI4

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB159808

Recombinant Human ZAN protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human ZAN protein (GST tag N-Terminus) (AB159808)

  • 0
  • 0
Proteins & Peptides

AB159886

Recombinant Human ZP2 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human ZP2 protein (GST tag N-Terminus) (AB159886)

  • 0
  • 0
Proteins & Peptides

AB160078

Recombinant Human DBPA protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human DBPA protein (GST tag N-Terminus) (AB160078)

  • 0
  • 0
Proteins & Peptides

AB163077

Recombinant Human VNN3 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human VNN3 protein (GST tag N-Terminus) (AB163077)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLISFLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQPFLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":398,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9UBI4","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

STOML1 also known as stomatin-like protein 1 is a protein with a mass of approximately 37 kDa. It belongs to the stomatin family and is expressed in various tissues including the brain heart and skeletal muscle. As a membrane protein STOML1 plays a role in modulating ion channel activities and is often located in lipid-rich microdomains contributing to the cellular regulation of ion homeostasis.
Biological function summary

Stomatin-like protein 1 influences cell signaling and is involved in sensory perception processes. It is part of the stomatin protein complex where it interacts with other proteins to regulate ion channels and transporters. By modulating these channels STOML1 contributes to neural activities and possibly pain perception making it a critical component in the nervous system's functionality.

Pathways

Stomatin-like protein 1 functions in sensory transduction and ion transport pathways. It is linked with the regulation of acid-sensing ion channels (ASICs) which are essential for neuronal communication and pain sensation. STOML1 also interacts with proteins like acid-sensing ion channel subunits through these pathways suggesting a collaborative role in neural excitability and signal transmission.

Stomatin-like protein 1 has connections with neuropathic pain and dystrophy conditions. Altered expression or dysfunction of STOML1 may contribute to abnormal sensory transmission seen in neuropathic pain syndromes. Additionally its interaction with proteins such as ASICs could be implicated in muscular dystrophies highlighting the importance of STOML1 in maintaining proper muscular and neural function.
style
left-column

Specifications

Form

Liquid

style
left-column

General info

Function

May play a role in cholesterol transfer to late endosomes (PubMed : 19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed : 23082202).

Sequence similarities

Belongs to the band 7/mec-2 family.

style
left-column

Product protocols

style
left-column

Target data

May play a role in cholesterol transfer to late endosomes (PubMed : 19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed : 23082202).
See full target information STOML1
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com