Recombinant Human STOML1 protein (denatured)
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Recombinant Human STOML1 protein (denatured) is a Human Fragment protein, in the 79 to 398 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
SLP1, UNC24, MSTP019, STOML1, Stomatin-like protein 1, SLP-1, EPB72-like protein 1, Protein unc-24 homolog, Stomatin-related protein, STORP
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human STOML1 protein (denatured) (AB202205)
15% SDS-PAGE analysis of ab202205 (3 μg)
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Stomatin-like protein 1 influences cell signaling and is involved in sensory perception processes. It is part of the stomatin protein complex where it interacts with other proteins to regulate ion channels and transporters. By modulating these channels STOML1 contributes to neural activities and possibly pain perception making it a critical component in the nervous system's functionality.
Pathways
Stomatin-like protein 1 functions in sensory transduction and ion transport pathways. It is linked with the regulation of acid-sensing ion channels (ASICs) which are essential for neuronal communication and pain sensation. STOML1 also interacts with proteins like acid-sensing ion channel subunits through these pathways suggesting a collaborative role in neural excitability and signal transmission.
Specifications
Form
Liquid
General info
Function
May play a role in cholesterol transfer to late endosomes (PubMed : 19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed : 23082202).
Sequence similarities
Belongs to the band 7/mec-2 family.
Subcellular localisation
Late endosome membrane
Target data
Complementary Products
Product promise
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