Recombinant Human STYXL1 protein (DDDDK tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human STYXL1 protein (DDDDK tag N-Terminus) is a Human Full Length protein, in the 2 to 313 aa range, expressed in Baculovirus infected Sf9 cells, with >90%, suitable for SDS-PAGE.
View Alternative Names
DUSP24, MKSTYX, STYXL1, Serine/threonine/tyrosine-interacting-like protein 1, Dual specificity phosphatase inhibitor MK-STYX, Dual specificity protein phosphatase 24, Inactive dual specificity protein phosphatase MK-STYX, Map kinase phosphatase-like protein MK-STYX
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human STYXL1 protein (DDDDK tag N-Terminus) (AB271807)
SDS-PAGE analysis of 2 μg ab271807.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
STYXL1 functions in regulating cellular processes despite its lack of catalytic activity. STYXL1 is associated with the regulation of cell signaling pathways and may interact with signaling proteins. It plays a role in modulating cellular communication networks by possibly scaffolding interactions rather than direct enzymatic activity. STYXL1 might exist as part of a complex where it collaborates with other proteins to mediate signaling effects.
Pathways
Researchers associate STYXL1 with the ERK/MAPK signaling pathway which controls processes such as cell division and differentiation. In this pathway STYXL1 might interact with kinases like ERK1/2 although it does not act as a traditional signaling enzyme itself. Another important pathway is the apoptosis signaling where STYXL1 impacts cellular decisions of life and death. Its pseudo-phosphatase nature could influence the pathway interactions by binding to components within these networks thereby adjusting signaling output without dephosphorylating substrates.
Specifications
Form
Liquid
Additional notes
Affinity purified.
General info
Function
Catalytically inactive phosphatase (PubMed : 20180778, PubMed : 23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed : 20180778, PubMed : 23163895). Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed : 23163895). Inhibits PTPMT1 phosphatase activity (PubMed : 24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed : 21262771). May play a role in the formation of neurites during neuronal development (PubMed : 29250526).
Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
Subcellular localisation
Mitochondrion matrix
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com