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Recombinant human Superoxide Dismutase 1 protein (Active) is a Human Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for FuncS, SDS-PAGE.
Alternative names=Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1, SOD1
- Purity
>95% SDS-PAGE
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
FuncS, SDS-PAGE
- Biologically active
Yes
Consider this alternative
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application FuncS | Reactivity Expected | Dilution info - | Notes - |
Application SDS-PAGE | Reactivity Expected | Dilution info - | Notes - |
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Recombinant human Superoxide Dismutase 1 protein (Active) is a Human Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for FuncS, SDS-PAGE.
Alternative names=Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1, SOD1
Key facts
- Purity
>95% SDS-PAGE
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
FuncS, SDS-PAGE
- Biologically active
Yes
- Biological activity
This protein is fully biologically active when compared to standard. Activity tests were carried using ab65354.
The activity assay kit showed that the calculated activity was ~40,000 U/mg.
- Predicted molecular weight
16.8 kDa
- Accession
- P00441-1
- Protein length
Full Length
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: 10.269% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic
Specifications
- Form
Lyophilized
- Additional notes
> 95% SDS-PAGE. The Cu/Zn SOD is purified by proprietary chromatographic techniques.
General info
- Function
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
- Sequence similarities
Belongs to the Cu-Zn superoxide dismutase family.
- Post-translational modifications
Unlike wild-type protein, the pathogenic variants ALS1 Arg-38, Arg-47, Arg-86 and Ala-94 are polyubiquitinated by RNF19A leading to their proteasomal degradation. The pathogenic variants ALS1 Arg-86 and Ala-94 are ubiquitinated by MARCH5 leading to their proteasomal degradation.
- Subcellular localisation
Mitochondrion, Nucleus
Storage
- Shipped at conditions
Blue Ice
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 4802 Superoxide Dismutase (SOD), human recombinant. 4802-100 is the same size as the 100 µg size of ab112193.
Endotoxin Levels: <0.1 ng/mg.
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