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AB156963

Recombinant Human SURF2 protein (His tag N-Terminus)

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Recombinant Human SURF2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 256 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Surfeit locus protein 2, Surf-2, SURF2

1 Images
SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)

15% SDS-PAGE analysis of ab156963 (3 µg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q15527

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.04% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSELPGDVRAFLREHPSLRLQTDARKVRCILTGHELPCRLPELQVYTRGKKYQRLVRASPAFDYAEFEPHIVPSTKNPHQLFCKLTLRHINKCPEHVLRHTQGRRYQRALCKYEECQKQGVEYVPACLVHRRRRREDQMDGDGPRPREAFWEPTSSDEGGAASDDSMTDLYPPELFTRKDLGSTEDGDGTDDFLTDKEDEKAKPPREKATDEGRRETTVYRGLVQKRGKKQLGSLKKKFKSHHRKPKSFSSCKQPG","proteinLength":"Full Length","predictedMolecularWeight":"32 kDa","actualMolecularWeight":null,"aminoAcidEnd":256,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q15527","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

SURF2 also known as Surfeit 2 is a protein with an approximate mass of 28 kDa. It is a component of the surfeit gene cluster which is compact and does not include any common regulatory elements shared by its member genes. SURF2 is expressed in various tissues but has significant expression in the lung and kidney. The protein itself functions as part of the cellular machinery specifically in membrane trafficking though detailed mechanisms at the molecular level require further study.
Biological function summary

This protein is engaged in critical cellular processes such as the modulation of intracellular trafficking. SURF2 is associated with the endoplasmic reticulum and Golgi apparatus hinting at a role in vesicle movement between these organelles. It works in conjunction with other proteins like CLIMP-63 and Ergic-53 participating in the correct sorting and dispatching of cargo proteins.

Pathways

SURF2 functions as a cog within the ER-Golgi transport pathway. It ensures effective vesicular trafficking which is essential for protein processing and secretion. Proteins such as Rab1 and Sec23 relate to SURF2 by collaborating in maintaining the integrity and functionality of this transport mechanism. These pathways are fundamental for cellular homeostasis and protein quality control.

SURF2 exhibits potential links to certain respiratory diseases due to its expression profile in lung tissue. Researchers hypothesize that improper function or expression of SURF2 could influence conditions like chronic obstructive pulmonary disease (COPD). Furthermore connections between SURF2 and other proteins like alpha-1-antitrypsin indicate a potential involvement in conditions where protease inhibitor imbalance plays a critical role. Understanding these associations might help develop therapeutic strategies targeting these pathways.
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Specifications

Form

Liquid

Additional notes

ab156963 was purified using conventional chromatography techniques.

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General info

Sequence similarities

Belongs to the SURF2 family.

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Product protocols

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Target data

See full target information SURF2
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