Recombinant Human SYBL1/VAMP-7 protein is a Human Fragment protein, in the 1 to 188 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Images
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S M A I L F A V V A R G T T I L A K H A W C G G N F L E V T E Q I L A K I P S E N N K L T Y S H G N Y L F H Y I C Q D R I V Y L C I T D D D F E R S R A F N F L N E I K K R F Q T T Y G S R A Q T A L P Y A M N S E F S S V L A A Q L K H H S E N K G L D K V M E T Q A Q V D E L K G I M V R N I D L V A Q R G E R L E L L I D K T E N L V D S S V T F K T T S R N L A R A M C M K N L K
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
Alternative names
SYBL1, VAMP7, Vesicle-associated membrane protein 7, VAMP-7, Synaptobrevin-like protein 1, Tetanus-insensitive VAMP, Ti-VAMP
Recommended products
Recombinant Human SYBL1/VAMP-7 protein is a Human Fragment protein, in the 1 to 188 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- P51809-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S M A I L F A V V A R G T T I L A K H A W C G G N F L E V T E Q I L A K I P S E N N K L T Y S H G N Y L F H Y I C Q D R I V Y L C I T D D D F E R S R A F N F L N E I K K R F Q T T Y G S R A Q T A L P Y A M N S E F S S V L A A Q L K H H S E N K G L D K V M E T Q A Q V D E L K G I M V R N I D L V A Q R G E R L E L L I D K T E N L V D S S V T F K T T S R N L A R A M C M K N L K
- Accession
- P51809
- Protein length
- Fragment
- Predicted molecular weight
- 23 kDa
- Amino acids
- 1 to 188
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab131706 is purified using conventional chromatography techniques
General info
- Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.
- Sequence similarities
Belongs to the synaptobrevin family.
- Subcellular localisation
- Late endosome membrane, Lysosome membrane
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Previously labelled as SYBL1.
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human SYBL1/VAMP-7 protein (ab131706)
15% SDS-PAGE showing ab131706 at approximately 23.0 kDa (3µg).
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com