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AB131666

Recombinant Human SYCE3 protein

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Recombinant Human SYCE3 protein is a Human Full Length protein, in the 1 to 88 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

C22orf41, THEG2, SYCE3, Synaptonemal complex central element protein 3, Testis highly expressed gene 2 protein, THEG-2

1 Images
SDS-PAGE - Recombinant Human SYCE3 protein (AB131666)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SYCE3 protein (AB131666)

15% SDS-PAGE showing ab131666 at approximately 12.8 kDa (3μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

A1L190

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.03% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMDDADPEERNYDNMLKMLSDLNKDLEKLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFVNCKEEMEKNWQELLHETKQRL","proteinLength":"Full Length","predictedMolecularWeight":"12.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":88,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"A1L190","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Specifications

Form

Liquid

Additional notes

Purified using conventional chromatography techniques.

General info

Function

Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed : 36635604). Required for the assembly of the central element of the synaptonemal complex during meiosis, via remodeling of SYCP1 lattice structures and promoting recruitment of SYCE2-TEX12 and SYCE1-SIX60S1 complexes (PubMed : 36635604). Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes (By similarity). Chromosome loading appears to require SYCP1 (By similarity). Required for fertility and normal testis development (By similarity).

Subcellular localisation

Nucleus

Product protocols

Target data

Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed : 36635604). Required for the assembly of the central element of the synaptonemal complex during meiosis, via remodeling of SYCP1 lattice structures and promoting recruitment of SYCE2-TEX12 and SYCE1-SIX60S1 complexes (PubMed : 36635604). Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes (By similarity). Chromosome loading appears to require SYCP1 (By similarity). Required for fertility and normal testis development (By similarity).
See full target information SYCE3

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