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Recombinant Human Syndecan-1 protein (His tag) is a Human Fragment protein, in the 18 to 254 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Alternative names=Syndecan-1, SYND1, SDC, SDC1
- Purity
>90% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S H M Q P A L P Q I V A T N L P P E D Q D G S G D D S D N F S G S G A G A L Q D I T L S Q Q T P S T W K D T Q L L T A I P T S P E P T G L E A T A A S T S T L P A G E G P K E G E A V V L P E V E P G L T A R E Q E A T P R P R E T T Q L P T T H Q A S T T T A T T A Q E P A T S H P H R D M Q P G H H E T S T P A G P S Q A D L H T P H T E D G G P S A T E R A A E D G A S S Q L P A A E G S G E Q D F T F E T S G E N T A V V A V E P D R R N Q S P V D Q G A T G A S Q G L L D R K E V L G
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant Human Syndecan-1 protein (His tag) is a Human Fragment protein, in the 18 to 254 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Alternative names=Syndecan-1, SYND1, SDC, SDC1
Key facts
- Purity
>90% SDS-PAGE
- Expression system
Escherichia coli
- Tags
His tag N-Terminus
- Applications
SDS-PAGE, MS
- Biologically active
No
- Predicted molecular weight
27 kDa
- Amino acids
18 to 254
- Sequence
M G S S H H H H H H S S G L V P R G S H M G S H M Q P A L P Q I V A T N L P P E D Q D G S G D D S D N F S G S G A G A L Q D I T L S Q Q T P S T W K D T Q L L T A I P T S P E P T G L E A T A A S T S T L P A G E G P K E G E A V V L P E V E P G L T A R E Q E A T P R P R E T T Q L P T T H Q A S T T T A T T A Q E P A T S H P H R D M Q P G H H E T S T P A G P S Q A D L H T P H T E D G G P S A T E R A A E D G A S S Q L P A A E G S G E Q D F T F E T S G E N T A V V A V E P D R R N Q S P V D Q G A T G A S Q G L L D R K E V L G
- Accession
- P18827-1
- Protein length
Fragment
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl
Specifications
- Form
Liquid
- Additional notes
ab124600 is purified by using conventional chromatography techniques.
General info
- Function
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
- Sequence similarities
Belongs to the syndecan proteoglycan family.
- Post-translational modifications
Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
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