Recombinant Human TATDN1 protein (His tag)
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Recombinant Human TATDN1 protein (His tag) is a Human Full Length protein, in the 1 to 297 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
CDA11, TATDN1, Deoxyribonuclease TATDN1, Hepatocarcinoma high expression protein
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human TATDN1 protein (His tag) (AB202214)
15% SDS PAGE analysis of 3 μg ab202214
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TATDN1 participates in apoptosis wherein it promotes the degradation of nuclear DNA during cell death. TATDN1 associates with complexes involving DNA repair and maintenance indicating its role in maintaining genomic integrity. The protein's ability to localize in different cellular compartments suggests its involvement in multiple cellular processes further highlighting its functional versatility in cells.
Pathways
TATDN1 engages in processes linked to both DNA damage response and apoptosis. It operates within the apoptosis pathway interacting with proteins like caspases which are responsible for the execution phase of cell apoptosis. In the context of DNA repair pathways TATDN1 may associate with proteins involved in detecting and rectifying DNA strand irregularities linking it to a network that enhances cell survival under stress.
Specifications
Form
Liquid
Additional notes
ab202214 was purified using conventional chromatography.
General info
Function
Deoxyribonuclease which catalyzes (in vitro) the decatenation of kinetoplast DNA, which are circular DNA catenated to each other, producing linear DNA molecules (By similarity). Plays an important role in chromosomal segregation and cell cycle progression during eye development probably via its DNA decatenation activity (By similarity).
Sequence similarities
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
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