Recombinant Human Tbx20 protein

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Tbx20 influences cardiac development and morphogenesis. It belongs to the T-box gene family which is integral to various developmental processes. Tbx20 forms complexes with other proteins including Nkx2-5 and Gata4 to modulate gene expression critical for heart tube formation and chamber differentiation. The Tbx20-containing complexes ensure proper cardiac structural and functional formation influencing cell fate decisions and tissue patterning.

Pathways

Tbx20 functions in cardiac and neural development pathways. In cardiac pathways it collaborates with signaling molecules such as Bmp and Wnt to regulate heart development and growth. Tbx20 interacts closely with other T-box proteins like Tbx2 and Tbx5 through these pathways orchestrating complex gene networks that ensure normal heart morphogenesis. In neural pathways Tbx20 regulates the differentiation of neural crest cells illustrating its versatility in multiple developmental contexts.