Recombinant Human TDGF1P3 protein (His tag) is a Human Full Length protein, in the 31 to 188 aa range, expressed in Mammalian, with >85% purity and suitable for SDS-PAGE.
L G H Q E F A R P S R G D L A F R D D S I W P Q E E P A I R P R S S Q R V L P M G I Q H S K E L N R T C C L N G G T C M L E S F C A C P P S F Y G R N C E H D V R K E N C G S V P H D T W L P K K C S L C K C W H G Q L R C F P Q A F L P G C D G L V M D E H L V A S R T P E L P P S A R T T T F M L A G I C L S I Q S Y Y
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.
CRIPTO-3, TDGF1P3, TDGF2, TDGF3, CRIPTO3, Putative protein CRIPTO3, Cripto-3 growth factor, Epidermal growth factor-like cripto protein CR3, Teratocarcinoma-derived growth factor 1 pseudogene 3, Teratocarcinoma-derived growth factor 3
Recombinant Human TDGF1P3 protein (His tag) is a Human Full Length protein, in the 31 to 188 aa range, expressed in Mammalian, with >85% purity and suitable for SDS-PAGE.
pH: 7.2 - 7.4
Constituents: PBS, 6% Trehalose
Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.
Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
TDGF1P3 also known as teratocarcinoma-derived growth factor 1 pseudogene 3 is a pseudogene which means it does not encode a functional protein. TDGF1P3 doesn’t produce proteins directly involved in any cellular functions but may still participate in regulatory activities affecting gene expression. Researchers typically locate expressions of pseudogenes such as TDGF1P3 in various tissues including developmental tissues even though the exact mass of the pseudogene product is not available due to its non-coding nature.
Pseudogenes like TDGF1P3 participate in gene regulation processes even though they do not produce proteins. They can contribute regulatory RNA molecules and can act as decoys in gene expression modulation. TDGF1P3 does not form part of a complex but may still influence the biological landscape by interacting with other functional gene counterparts and their networks often involving parent genes like TDGF1.
Although TDGF1P3 does not directly encode proteins participating in pathways its involvement in the gene regulatory landscape can influence specific pathways. For instance TDGF1 the parent gene involves the Nodal signaling pathway which is important for embryonic development. TDGF1P3 may modulate functions by affecting regulatory mechanisms therefore influencing pathways indirectly along with potential interactions with proteins like Cripto.
Pseudogenes like TDGF1P3 can impact disease phenotypes through their regulatory roles. TDGF1P3 might relate to disorders involving aberrant gene expression potentially influencing developmental diseases or cancers where its parent gene TDGF1 is implicated. Investigating these connections helps understand disease mechanisms and discover how pseudogenes such as TDGF1P3 might act as regulatory elements within the disease context.
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