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Recombinant Human TDGF1P3 protein (His tag) is a Human Full Length protein, in the 31 to 188 aa range, expressed in Mammalian, with >85% purity and suitable for SDS-PAGE.

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Key facts

Purity

>85% SDS-PAGE

Expression system

Mammalian

Tags

His tag C-Terminus

Applications

SDS-PAGE

Biologically active

No

Amino acid sequence

L G H Q E F A R P S R G D L A F R D D S I W P Q E E P A I R P R S S Q R V L P M G I Q H S K E L N R T C C L N G G T C M L E S F C A C P P S F Y G R N C E H D V R K E N C G S V P H D T W L P K K C S L C K C W H G Q L R C F P Q A F L P G C D G L V M D E H L V A S R T P E L P P S A R T T T F M L A G I C L S I Q S Y Y

Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

Alternative names

Recommended products

Recombinant Human TDGF1P3 protein (His tag) is a Human Full Length protein, in the 31 to 188 aa range, expressed in Mammalian, with >85% purity and suitable for SDS-PAGE.

Alternative names

Key facts

Purity

>85% SDS-PAGE

Expression system

Mammalian

Applications

SDS-PAGE

Accession
P51864-1
Animal free

No

Species

Human

Concentration
Loading...
Storage buffer

pH: 7.2 - 7.4
Constituents: PBS, 6% Trehalose

Sequence info

Amino acid sequence

L G H Q E F A R P S R G D L A F R D D S I W P Q E E P A I R P R S S Q R V L P M G I Q H S K E L N R T C C L N G G T C M L E S F C A C P P S F Y G R N C E H D V R K E N C G S V P H D T W L P K K C S L C K C W H G Q L R C F P Q A F L P G C D G L V M D E H L V A S R T P E L P P S A R T T T F M L A G I C L S I Q S Y Y

Accession

P51864

Protein length

Full Length

Amino acids

31 to 188

Nature

Recombinant

Tags

His tag C-Terminus

Specifications

Form

Liquid

General info

Function

Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

Sequence similarities

Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

TDGF1P3 also known as teratocarcinoma-derived growth factor 1 pseudogene 3 is a pseudogene which means it does not encode a functional protein. TDGF1P3 doesn’t produce proteins directly involved in any cellular functions but may still participate in regulatory activities affecting gene expression. Researchers typically locate expressions of pseudogenes such as TDGF1P3 in various tissues including developmental tissues even though the exact mass of the pseudogene product is not available due to its non-coding nature.

Biological function summary

Pseudogenes like TDGF1P3 participate in gene regulation processes even though they do not produce proteins. They can contribute regulatory RNA molecules and can act as decoys in gene expression modulation. TDGF1P3 does not form part of a complex but may still influence the biological landscape by interacting with other functional gene counterparts and their networks often involving parent genes like TDGF1.

Pathways

Although TDGF1P3 does not directly encode proteins participating in pathways its involvement in the gene regulatory landscape can influence specific pathways. For instance TDGF1 the parent gene involves the Nodal signaling pathway which is important for embryonic development. TDGF1P3 may modulate functions by affecting regulatory mechanisms therefore influencing pathways indirectly along with potential interactions with proteins like Cripto.

Associated diseases and disorders

Pseudogenes like TDGF1P3 can impact disease phenotypes through their regulatory roles. TDGF1P3 might relate to disorders involving aberrant gene expression potentially influencing developmental diseases or cancers where its parent gene TDGF1 is implicated. Investigating these connections helps understand disease mechanisms and discover how pseudogenes such as TDGF1P3 might act as regulatory elements within the disease context.

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