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AB276533

Recombinant Human TEM8/ATR protein (Fc Chimera)

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Recombinant Human TEM8/ATR protein (Fc Chimera) is a Human Fragment protein, in the 1 to 321 aa range, expressed in HEK 293 cells, with >92%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

ATR, TEM8, ANTXR1, Anthrax toxin receptor 1, Tumor endothelial marker 8

1 Images
SDS-PAGE - Recombinant Human TEM8/ATR protein (Fc Chimera) (AB276533)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human TEM8/ATR protein (Fc Chimera) (AB276533)

SDS-PAGE analysis of ab276533

Key facts

Purity

>92% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9H6X2

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

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Primary Antibodies

AB241067

Anti-TEM8/ATR antibody [EPNCI-R173-37]

20ul selling size|RabMAb|Recombinant

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Proteins & Peptides

AB204140

Recombinant Human ATR protein

SDS-PAGE - Recombinant Human ATR protein (AB204140)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Primary Antibodies

AB2905

Anti-ATR antibody

Western blot - Anti-ATR antibody (AB2905)

  • 4
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"linker":null,"sequence":"MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGS","proteinLength":"Fragment","predictedMolecularWeight":"59.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":321,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q9H6X2","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]
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Properties and storage information

Form
Lyophilized
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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General info

Function

Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton and thereby plays an important role in normal extracellular matrix (ECM) homeostasis. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. May also act as a receptor for PLAU. Upon ligand binding, stimulates the phosphorylation of EGFR and ERK1/2 (PubMed : 30241478).. (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis.. (Microbial infection) Mediates cell entry of Seneca Valley virus (SVV) when glycosylated.

Sequence similarities

Belongs to the ATR family.

Post-translational modifications

Glycosylated. Glycosylation is essential for Seneca Valley virus (SVV) attachment and entry.. Phosphorylated upon PLAU binding.

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Product protocols

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Target data

Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton and thereby plays an important role in normal extracellular matrix (ECM) homeostasis. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. May also act as a receptor for PLAU. Upon ligand binding, stimulates the phosphorylation of EGFR and ERK1/2 (PubMed : 30241478).. (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis.. (Microbial infection) Mediates cell entry of Seneca Valley virus (SVV) when glycosylated.
See full target information ANTXR1
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Product promise

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