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Recombinant human TGF beta 3 protein (Active) is a Human Fragment protein, in the 301 to 412 aa range, expressed in Escherichia coli, with >98% purity and suitable for SDS-PAGE, FuncS, HPLC, WB.
Alternative names=Transforming growth factor beta-3 proprotein, TGFB3
- Purity
>98% SDS-PAGE
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
SDS-PAGE, FuncS, HPLC, WB
- Biologically active
Yes
- Sequence
A L D T N Y C F R N L E E N C C V R P L Y I D F R Q D L G W K W V H E P K G Y Y A N F C S G P C P Y L R S A D T T H S T
V L G L Y N T L N P E A S A S P C C V P Q D L E P L T I L Y Y V G R T P K V E Q L S N M V V K S C K C S
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Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Application HPLC | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes Ab52313 can be used as a WB positive control in conjunction with ab15537. |
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Recombinant human TGF beta 3 protein (Active) is a Human Fragment protein, in the 301 to 412 aa range, expressed in Escherichia coli, with >98% purity and suitable for SDS-PAGE, FuncS, HPLC, WB.
Alternative names=Transforming growth factor beta-3 proprotein, TGFB3
Key facts
- Purity
>98% SDS-PAGE
- Expression system
Escherichia coli
- Tags
Tag free
- Applications
SDS-PAGE, FuncS, HPLC, WB
- Biologically active
Yes
- Biological activity
ab52313 is fully biologically active.
The ED50 was determined by cytotoxicity assay using the WHO standard 98/608 as a direct comparison is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 108 units/mg.
- Predicted molecular weight
25.5 kDa
- Amino acids
301 to 412
- Sequence
A L D T N Y C F R N L E E N C C V R P L Y I D F R Q D L G W K W V H E P K G Y Y A N F C S G P C P Y L R S A D T T H S T
V L G L Y N T L N P E A S A S P C C V P Q D L E P L T I L Y Y V G R T P K V E Q L S N M V V K S C K C S- Accession
- P10600-1
- Protein length
Fragment
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
Constituents: 20% Ethanol, 0.06% Acetic acid buffer
Specifications
- Form
Liquid
- Additional notes
>98% HPLC analyses
General info
- Function
Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
- Sequence similarities
Belongs to the TGF-beta family.
- Post-translational modifications
Transforming growth factor beta-3 proprotein: The precursor proprotein is cleaved in the Golgi apparatus to form Transforming growth factor beta-3 (TGF-beta-3) and Latency-associated peptide (LAP) chains, which remain non-covalently linked, rendering TGF-beta-3 inactive.
Storage
- Shipped at conditions
Blue Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA)
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Notes
This product is manufactured by BioVision, an Abcam company and was previously called 4344 TGF-beta3, human recombinant. 4344-5 is the same size as the 5 μg size of ab52313.
Endotoxin level: <0.1 ng/μg.
Centrifuge the vial prior to opening.
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