Recombinant Human TMEM156 protein (His tag)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

TMEM156 also known as Transmembrane Protein 156 is a protein of approximately 32 kDa. It has a series of transmembrane domains that span the cell membrane. You will find TMEM156 mainly expressed in human tissues including the heart liver and kidney. The protein potentially plays a role in the formation or regulation of membrane structures or transport activities although specific detailed functions remain under investigation.

Biological function summary

Insights into TMEM156 suggest involvement in cellular homeostasis yet it is not fully understood. Research indicates that it might interact with other proteins to form a complex that contributes to cellular regulatory mechanisms. TMEM156 might play a subtle role in maintaining the structural integrity or signaling efficiency of cells. However scientific investigation still seeks to unravel the full biological impacts of this protein.

Pathways

Investigators have started to identify potential involvement of TMEM156 in membrane trafficking or signal transduction pathways. It may relate functionally to the Wnt signaling pathway which is important for regulating cell fate and proliferation. Within these pathways TMEM156 is thought to interact with proteins such as β-catenin though much about these interactions requires further elucidation.

TMEM156 has shown correlation with cardiovascular diseases especially where membrane integrity is compromised. Dysregulation of TMEM156 expression seems to be linked with congenital heart defects. Additionally research suggests a potential connection with disorders involving liver dysfunction. These associations underline the need for further studies to better understand the exact mechanisms by which TMEM156 interaction with proteins like β-catenin impacts disease progression.