Recombinant Human TSTD1 protein
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Recombinant Human TSTD1 protein is a Human Full Length protein, in the 1 to 115 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
KAT, TSTD1, Thiosulfate:glutathione sulfurtransferase, TST
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human TSTD1 protein (AB104819)
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human TSTD1 protein (AB104819)
15% SDS-PAGE analysis of 3μg ab104819.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TSTD1 supports cellular processes by facilitating the conversion of thiosulfate to sulfite and hydrogen sulfide contributing to the metabolism of sulfur. Although not identified as part of a large protein complex TSTD1 interacts with other enzymes in networks managing sulfur metabolism. This interaction emphasizes its role in pathways ensuring the balance of sulfur species which are critical for detoxifying potentially harmful compounds.
Pathways
TSTD1 holds relevance in sulfur metabolism and the hydrogen sulfide signaling pathway. It impacts the sulfur relay system by working alongside proteins like rhodanese and thioredoxin which both participate in similar sulfur transfer processes. By influencing the production and regulation of hydrogen sulfide TSTD1 may affect cellular signaling and defense mechanisms against oxidative stress.
Specifications
Form
Liquid
Additional notes
ab104819 is purified using conventional chromatography techniques.
General info
Function
Thiosulfate : glutathione sulfurtransferase (TST) required to produce S-sulfanylglutathione (GSS(-)), a central intermediate in hydrogen sulfide metabolism (PubMed : 24981631). Provides the link between the first step in mammalian H(2)S metabolism performed by the sulfide : quinone oxidoreductase (SQOR) which catalyzes the conversion of H(2)S to thiosulfate, and the sulfur dioxygenase (SDO) which uses GSS(-) as substrate (PubMed : 24981631). The thermodynamic coupling of the irreversible SDO and reversible TST reactions provides a model for the physiologically relevant reaction with thiosulfate as the sulfane donor (PubMed : 24981631). GSS(-) spontaneously reacts with glutathione to form glutathione disulfide (Probable).
Target data
Complementary Products
Product promise
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