Recombinant Human UNC119B protein (His tag N-Terminus)
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Recombinant Human UNC119B protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 251 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
Protein unc-119 homolog B, UNC119B
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human UNC119B protein (His tag N-Terminus) (AB123153)
15% SDS-PAGE analysis of ab123153 (3 μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The ability of UNC119B to bind lipid-modified proteins plays a role in ensuring efficient protein trafficking within cells. It is part of a transport complex that delivers lipidated proteins to their correct cellular destinations. This function supports membrane dynamics by verifying that signaling molecules reach necessary cellular compartments. Interaction with ARL proteins helps stabilize the transport complex and facilitates its membrane association.
Pathways
UNC119B functions significantly in the phototransduction and neuronal signaling pathways. It participates in the ciliary transport pathway which is important for the movement of proteins inside photoreceptor cells. UNC119B interacts with proteins like RPGR which is associated with proper functioning and maintenance of photoreceptor cells. This involvement is essential for preserving cell signaling and response mechanisms.
Specifications
Form
Liquid
Additional notes
ab123153 was purified by using conventional chromatography techniques.
General info
Function
Myristoyl-binding protein that acts as a cargo adapter : specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.
Sequence similarities
Belongs to the PDE6D/unc-119 family.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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