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AB290079

Recombinant Human UPAR Protein (Active)

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Recombinant Human UPAR Protein (Active) is a Human Fragment protein, in the 23 to 303 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for FuncS.

View Alternative Names

CD87, MO3, UPAR, PLAUR, Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3

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Biological Activity - Recombinant Human UPAR Protein (Active) (AB290079)
  • Biological Activity

Lab

Biological Activity - Recombinant Human UPAR Protein (Active) (AB290079)

Loaded Human UPA/Urokinase, His Tag on Ni2+ Biosensor can bind Human UPAR with an affinity constant of 0.82 nM as determined in BLI assay (GatorBio Prime).

Mass Spectrometry - Recombinant Human UPAR Protein (Active) (AB290079)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human UPAR Protein (Active) (AB290079)

Mass determination by ESI-TOF.

Predicted MW is 31373.15 Da. (+/- 10 Da by ESI-TOF). Observed MW is 31220.92 Da.

M -156 Da, due to Arginine truncation

HPLC - Recombinant Human UPAR Protein (Active) (AB290079)
  • HPLC

Supplier Data

HPLC - Recombinant Human UPAR Protein (Active) (AB290079)

HPLC analysis of ab290079

SDS-PAGE - Recombinant Human UPAR Protein (Active) (AB290079)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human UPAR Protein (Active) (AB290079)

SDS-PAGE analysis of ab290079

Key facts

Purity

>95% HPLC

Endotoxin level

<0.005 EU/µg

Expression system

HEK 293 cells

Tags

Tag free

Applications

FuncS

applications

Biologically active

Yes

Biological activity

Loaded Human UPA/Urokinase, His Tag on Ni2+ Biosensor can bind Human UPAR with an affinity constant of 0.82 nM as determined in BLI assay (GatorBio Prime).

Accession

Q03405

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

Storage buffer

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" } } }

Sequence info

[{"sequence":"LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYR","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":303,"aminoAcidStart":23,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q03405","tags":[]}]

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
True

Specifications

Form

Lyophilized

General info

Function

Acts as a receptor for urokinase plasminogen activator (PubMed : 15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

Product protocols

Target data

Acts as a receptor for urokinase plasminogen activator (PubMed : 15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
See full target information PLAUR

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