Recombinant Human UPAR Protein (Active)
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- What is this?
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Recombinant Human UPAR Protein (Active) is a Human Fragment protein, in the 23 to 303 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for FuncS.
View Alternative Names
CD87, MO3, UPAR, PLAUR, Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3
- Biological Activity
Lab
Biological Activity - Recombinant Human UPAR Protein (Active) (AB290079)
Loaded Human UPA/Urokinase, His Tag on Ni2+ Biosensor can bind Human UPAR with an affinity constant of 0.82 nM as determined in BLI assay (GatorBio Prime).
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Human UPAR Protein (Active) (AB290079)
Mass determination by ESI-TOF.
Predicted MW is 31373.15 Da. (+/- 10 Da by ESI-TOF). Observed MW is 31220.92 Da.
M -156 Da, due to Arginine truncation
- HPLC
Supplier Data
HPLC - Recombinant Human UPAR Protein (Active) (AB290079)
HPLC analysis of ab290079
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human UPAR Protein (Active) (AB290079)
SDS-PAGE analysis of ab290079
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Specifications
Form
Lyophilized
General info
Function
Acts as a receptor for urokinase plasminogen activator (PubMed : 15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Target data
Product promise
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