JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB236178

Recombinant Human Versican protein (Tagged)

Be the first to review this product! Submit a review

|

(1 Publication)

Recombinant Human Versican protein (Tagged) is a Human Fragment protein, in the 3089 to 3354 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

View Alternative Names

CSPG2, VCAN, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, PG-M, Chondroitin sulfate proteoglycan 2, GHAP

1 Images
SDS-PAGE - Recombinant Human Versican protein (Tagged) (AB236178)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Versican protein (Tagged) (AB236178)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab236178.

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P13611

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"GPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMN","proteinLength":"Fragment","predictedMolecularWeight":"47.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":3354,"aminoAcidStart":3089,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P13611","tags":[]}]
style
left-column

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

Specifications

Form

Liquid

style
left-column

General info

Function

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.

Sequence similarities

Belongs to the aggrecan/versican proteoglycan family.

Post-translational modifications

Phosphorylated by FAM20C in the extracellular medium.. Proteolytically cleaved by ADAMTS5 and ADAMTS15 in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.

style
left-column

Product protocols

style
left-column

Target data

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
See full target information VCAN
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 300:107968 PubMed39510178

2024

Versican binds collagen via its G3 domain and regulates the organization and mechanics of collagenous matrices.

Applications

Unspecified application

Species

Unspecified reactive species

Dongning Chen,Yu Du,Jessica Llewellyn,Arkadiusz Bonna,Biao Zuo,Paul A Janmey,Richard W Farndale,Rebecca G Wells
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB177480

Anti-Versican antibody [EPR12277]

RabMAb|Recombinant|20ul selling size

Western blot - Anti-Versican antibody [EPR12277] (AB177480)

  • 4
  • 3
Assay Kits

AB279409

Mouse Versican ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse Versican ELISA Kit (AB279409)

  • 0
  • 0
Proteins & Peptides

AB39784

Human Versican peptide

  • 0
  • 0
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com