Recombinant Human VPAC2 protein (GST tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human VPAC2 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 438 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
VIP2R, VIPR2, Vasoactive intestinal polypeptide receptor 2, VIP-R-2, Helodermin-preferring VIP receptor, Pituitary adenylate cyclase-activating polypeptide type III receptor, VPAC2 receptor, PACAP type III receptor, PACAP-R-3, PACAP-R3, VPAC2R
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human VPAC2 protein (GST tag N-Terminus) (AB159805)
ab159805 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of potency PACAP38 = VIP > PACAP27 (PubMed : 35477937, PubMed : 8933357). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway (PubMed : 7811244, PubMed : 35477937, PubMed : 8933357). May be coupled to phospholipase C.
Sequence similarities
Belongs to the G-protein coupled receptor 2 family.
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com