Recombinant Human XTP3TPA protein is a Human Full Length protein, in the 1 to 170 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
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Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S H M S V A G G E I R G D T G G E D T A A P G R F S F S P E P T L E D I R R L H A E F A A E R D W E Q F H Q P R N L L L A L V G E V G E L A E L F Q W K T D G E P G P Q G W S P R E R A A L Q E E L S D V L I Y L V A L A A R C R V D L P L A V L S K M D I N R R R Y P A H L A R S S S R K Y T E L P H G A I S E D Q A V G P A D I P C D S T G Q T S T
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
Alternative names
XTP3TPA, CDA03, DCTPP1, dCTP pyrophosphatase 1, Deoxycytidine-triphosphatase 1, RS21C6, XTP3-transactivated gene A protein, dCTPase 1
Recommended products
Recombinant Human XTP3TPA protein is a Human Full Length protein, in the 1 to 170 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- Q9H773-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S H M S V A G G E I R G D T G G E D T A A P G R F S F S P E P T L E D I R R L H A E F A A E R D W E Q F H Q P R N L L L A L V G E V G E L A E L F Q W K T D G E P G P Q G W S P R E R A A L Q E E L S D V L I Y L V A L A A R C R V D L P L A V L S K M D I N R R R Y P A H L A R S S S R K Y T E L P H G A I S E D Q A V G P A D I P C D S T G Q T S T
- Accession
- Q9H773
- Protein length
- Full Length
- Predicted molecular weight
- 21.2 kDa
- Amino acids
- 1 to 170
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab119438 was purified using conventional chromatography techniques.
General info
- Function
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
- Subcellular localisation
- Mitochondrion, Nucleus
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
XTP3TPA also known as Diecloropyrophosphatase is part of a larger family of proteins involved in pyrophosphate hydrolysis. This protein has a mass of approximately 65 kDa. XTP3TPA expression occurs in several tissues with higher levels in liver and kidney. These tissues play a major role in metabolic processes which would likely relate to this protein's functions.
- Biological function summary
XTP3TPA functions to regulate cellular energy. These proteins also influence metabolic efficiency by hydrolyzing pyrophosphate to inorganic phosphate. XTP3TPA often operates within larger protein complexes to enhance its enzymatic role. This activity represents a common aspect of cellular metabolism impacting processes like ATP production.
- Pathways
XTP3TPA integrates into the ATP synthesis and nucleotide metabolism pathways. Within these pathways XTP3TPA sometimes collaborates with proteins such as ATP synthase coordinating energy production and utilization. Its presence in these pathways ensures proper energy allocation which is important for cellular survival and function.
- Associated diseases and disorders
XTP3TPA abnormalities link to metabolic disorders such as type 2 diabetes and metabolic syndrome. Disrupted function or expression of XTP3TPA might impact proteins like AMP-activated protein kinase (AMPK). This disruption can lead to metabolic imbalances necessitating more research into XTP3TPA for potential therapeutic targets.
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1 product image
SDS-PAGE - Recombinant Human XTP3TPA protein (ab119438)
12% SDS-PAGE Coomassie gel showing Anti-CD44 antibody [1M7.8.1] ab119348, 3μg.
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