Recombinant Human YKL-39 protein
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Recombinant Human YKL-39 protein is a Human Full Length protein, in the 27 to 390 aa range, expressed in HEK 293 cells, with >95%, < 0.1 EU/µg endotoxin level, suitable for SDS-PAGE, HPLC.
View Alternative Names
Chitinase-3-like protein 2, Chondrocyte protein 39, YKL-39, CHI3L2
Reactivity data
Product details
Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Previously labelled as CHI3L2.
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
YKL-39 plays an important role in tissue remodeling and repair especially within the cartilage matrix. It does not form part of a large protein complex but interacts with other matrix proteins to help maintain structural integrity and support cellular responses to tissue damage. YKL-39 contributes to cell proliferation and has been found to affect inflammation pathways making it an important molecule in both normal physiological processes and in response to stress or injury.
Pathways
YKL-39 functions engage in critical roles within the extracellular matrix and inflammatory response pathways. Specifically it associates with the ECM as it relates to cartilage maintenance where it potentially interacts with other proteins such as YKL-40 another chitinase-like protein. YKL-39's involvement is significant in signaling cascades that mediate extracellular matrix homeostasis and modulate inflammation important for maintaining tissue structure and function.
Specifications
Form
Lyophilized
Additional notes
ab152034 was determined to be >95% pure by SEC-HPLC and reducing SDS-PAGE.
General info
Function
Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Sequence similarities
Belongs to the glycosyl hydrolase 18 family.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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