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AB164919

Recombinant Human Zinc finger protein 276

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Recombinant Human Zinc finger protein 276 is a Human Full Length protein, in the 1 to 373 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

CENP-Z, ZFP276, ZNF477, ZNF276, Zinc finger protein 276, Zfp-276, Zinc finger protein 477

1 Images
SDS-PAGE - Recombinant Human Zinc finger protein 276 (AB164919)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human Zinc finger protein 276 (AB164919)

ab164919 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q8N554

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as ZNF276.
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Sequence info

[{"sequence":"MDTSSSCKAFLLDSALAVKWPRDKETAPRLPQHRGWNPGDAPQTSQGRGTGTPVGAETKTLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGQLGEKQLPSSTSDDRVKDEFSDLSEGDVLSEDENDKKQNAQSSDESFEPYPERKVSGKKSESKEAKKSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSPSVTTEGQAVKPEPT","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":373,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q8N554","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Zinc finger protein 276 also known as ZNF276 is a transcription factor characterized by its zinc finger motifs which facilitate its binding to DNA. It weighs approximately 63 kilodaltons. ZNF276 plays a role in gene regulation and its expression occurs in various tissues including the brain and heart. It localizes predominantly in the nucleus where it modulates gene expression by interacting with other molecules and compounds.
Biological function summary

Zinc finger protein 276 functions in cellular processes through regulation of transcription. It may exist as part of a larger protein complex that helps in the control of specific genes involved in development and differentiation. The protein possibly interacts with other transcription factors to influence growth-related genes but further details of its partners remain under investigation. New studies continue to clarify how ZNF276 can directly affect chromatin remodeling and gene accessibility.

Pathways

Zinc finger protein 276 acts within the context of pathways related to gene expression modulation and cell cycle regulation. It may interact within signaling pathways like Wnt signaling known for its role in embryonic development and cancer. ZNF276 has relationships with other transcriptional regulators such as TCF/LEF family proteins involved in Wnt signaling pathways providing an intersection point for transcriptional control processes.

Zinc finger protein 276 has links to certain cancers and neurodevelopmental disorders. Its abnormal expression or mutations can impact the regulation of genes involved in these conditions. ZNF276's role in gene expression control places it as a node of intersection with other proteins like C-MYC commonly dysregulated in cancers. More research is required to delineate its specific contributions to these disease mechanisms and the interactions with associated proteins.
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Specifications

Form

Liquid

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General info

Function

May be involved in transcriptional regulation.

Subcellular localisation

Nucleus

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Product protocols

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Target data

May be involved in transcriptional regulation.
See full target information ZNF276
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