Skip to main content

Recombinant Human ZNF266 protein is a Human Fragment protein, in the 22 to 254 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.

Be the first to review this product! Submit a review

Key facts

Purity
>95%
Expression system
Escherichia coli
Tags
His-DHFR tag N-Terminus
Applications
SDS-PAGE
Biologically active
No

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Target data

Function

May be involved in transcriptional regulation.

Alternative names

Recombinant Human ZNF266 protein is a Human Fragment protein, in the 22 to 254 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE.

Key facts

Purity
>95%
Expression system
Escherichia coli
Applications
SDS-PAGE
Accession
Q14584-1
Animal free
No
Species
Human
Reconstitution
Reconstitute in water
Concentration
Loading...
Storage buffer

Constituents: 0.58% Sodium chloride, 0.32% Tris HCl

Sequence info

Amino acid sequence

Accession
Q14584
Protein length
Fragment
Predicted molecular weight
26.2 kDa
Amino acids
22 to 254
Nature
Recombinant
Tags
His-DHFR tag N-Terminus

Specifications

Form
Lyophilized
Additional notes

Purity determined to be >95% by SDS-PAGE.

General info

Function

May be involved in transcriptional regulation.

Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Subcellular localisation
Nucleus

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

ZNF266 also referred to as Zinc Finger Protein 266 is a protein that functions as a transcription factor. It has a known mass of approximately 77 kDa. This protein contains zinc finger motifs which enable it to bind to DNA and influence gene transcription. ZNF266 is expressed across multiple tissues with significant expression levels identified in the kidney brain and heart. These zinc finger proteins play a role in the regulation of transcriptional processes within these tissues.

Biological function summary

Zinc Finger Protein 266 impacts gene expression by binding to specific DNA sequences thereby regulating the transcription process. Although it doesn't necessarily form part of any specific protein complex ZNF266 can interact with other transcription factors and proteins modulating their functions. It may influence the expression of genes involved in cellular growth and differentiation indicating its role in fundamental cellular processes.

Pathways

Zinc Finger Protein 266 takes part in the transcriptional regulation pathways. It plays a role in cellular pathways like the Wnt signaling pathway known for regulating cell proliferation and differentiation and interacts with other proteins such as β-catenin. ZNF266 has also shown interactions in pathways related to the p53 signaling which involves tumor suppression and cell cycle regulation.

Associated diseases and disorders

Zinc Finger Protein 266 associates with potential roles in cancer and neurodevelopmental disorders. Alterations in its expression levels or function can contribute to tumorigenesis where it may interact with proteins like p53 influencing tumor suppression mechanisms. Changes in ZNF266 expression have also been noted in certain neurodevelopmental conditions likely affecting pathways and proteins involved in neural growth and development.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

0 product images

    Downloads

    Product protocols

    For this product, it's our understanding that no specific protocols are required. You can:

    Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

    For licensing inquiries, please contact partnerships@abcam.com