Recombinant Human ZNF266 protein (His-DHFR tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF266 also referred to as Zinc Finger Protein 266 is a protein that functions as a transcription factor. It has a known mass of approximately 77 kDa. This protein contains zinc finger motifs which enable it to bind to DNA and influence gene transcription. ZNF266 is expressed across multiple tissues with significant expression levels identified in the kidney brain and heart. These zinc finger proteins play a role in the regulation of transcriptional processes within these tissues.

Biological function summary

Zinc Finger Protein 266 impacts gene expression by binding to specific DNA sequences thereby regulating the transcription process. Although it doesn't necessarily form part of any specific protein complex ZNF266 can interact with other transcription factors and proteins modulating their functions. It may influence the expression of genes involved in cellular growth and differentiation indicating its role in fundamental cellular processes.

Pathways

Zinc Finger Protein 266 takes part in the transcriptional regulation pathways. It plays a role in cellular pathways like the Wnt signaling pathway known for regulating cell proliferation and differentiation and interacts with other proteins such as β-catenin. ZNF266 has also shown interactions in pathways related to the p53 signaling which involves tumor suppression and cell cycle regulation.

Zinc Finger Protein 266 associates with potential roles in cancer and neurodevelopmental disorders. Alterations in its expression levels or function can contribute to tumorigenesis where it may interact with proteins like p53 influencing tumor suppression mechanisms. Changes in ZNF266 expression have also been noted in certain neurodevelopmental conditions likely affecting pathways and proteins involved in neural growth and development.