Recombinant Human ZNF32 protein (denatured) is a Human Full Length protein, in the 1 to 273 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
>85% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
M G S S H H H H H H S S G L V P R G S H M G S M F G F P T A T L L D C H G R Y A Q N V A F F N V M T E A H H K Y D H S E A T G S S S W D I Q N S F R R E K L E Q K S P D S K T L Q E D S P G V R Q R V Y E C Q E C G K S F R Q K G S L T L H E R I H T G Q K P F E C T H C G K S F R A K G N L V T H Q R I H T G E K P Y Q C K E C G K S F S Q R G S L A V H E R L H T G Q K P Y E C A I C Q R S F R N Q S N L A V H R R V H S G E K P Y R C D Q C G K A F S Q K G S L I V H I R V H T G L K P Y A C T Q C R K S F H T R G N C I L H G K I H T G E T P Y L C G Q C G K S F T Q R G S L A V H Q R S C S Q R L T L
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
KOX30, ZNF32, Zinc finger protein 32, C2H2-546, Zinc finger protein KOX30
Recombinant Human ZNF32 protein (denatured) is a Human Full Length protein, in the 1 to 273 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
>85% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
No
Human
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl
M G S S H H H H H H S S G L V P R G S H M G S M F G F P T A T L L D C H G R Y A Q N V A F F N V M T E A H H K Y D H S E A T G S S S W D I Q N S F R R E K L E Q K S P D S K T L Q E D S P G V R Q R V Y E C Q E C G K S F R Q K G S L T L H E R I H T G Q K P F E C T H C G K S F R A K G N L V T H Q R I H T G E K P Y Q C K E C G K S F S Q R G S L A V H E R L H T G Q K P Y E C A I C Q R S F R N Q S N L A V H R R V H S G E K P Y R C D Q C G K A F S Q K G S L I V H I R V H T G L K P Y A C T Q C R K S F H T R G N C I L H G K I H T G E T P Y L C G Q C G K S F T Q R G S L A V H Q R S C S Q R L T L
Full Length
33.4 kDa
1 to 273
Recombinant
His tag N-Terminus
Liquid
May be involved in transcriptional regulation.
Belongs to the krueppel C2H2-type zinc-finger protein family.
Nucleus
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
This supplementary information is collated from multiple sources and compiled automatically.
ZNF32 also known as Zinc Finger Protein 32 acts mechanically as a transcription factor. This protein with a molecular mass around 59 kDa binds to specific DNA sequences influencing gene expression. Researchers have identified its robust expression in several tissues including the brain liver and spleen. ZNF32 plays a role in gene regulation and its zinc finger motifs allow it to interact with DNA enabling transcriptional regulation functions.
ZNF32 regulates the expression of various genes involved in cell survival and apoptosis. It does not form part of a known complex but its activity influences important cellular processes. This regulatory capacity impacts cellular responses to stress and contributes to homeostasis within different cellular environments. Its ability to modulate gene expression links it to the control of cell proliferation and differentiation.
ZNF32 becomes important in the apoptosis and cell cycle regulation pathways. It interacts with other transcription factors and proteins like p53 in apoptosis signaling pathways. This involvement in the recycling of cellular components places ZNF32 in direct relation with multiple signaling cascades that sustain cellular function and survival. These interactions highlight its necessity in maintaining cellular integrity and preventing unwanted cell death.
ZNF32 shows association with cancer and neurodegenerative disorders. Aberrant expression or mutations in the ZNF32 gene may correlate with increased tumorigenesis largely through its interaction with p53 during apoptosis. ZNF32 also demonstrates a connection to Alzheimer's disease likely influencing pathways with associated proteins like tau. Understanding these interactions aids in recognizing how ZNF32 modifications can contribute to pathology.
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15% SDS-PAGE analysis of 3 μg ab181934.
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