Recombinant Human ZNF320 protein (His-DHFR tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF320 also known as Zinc Finger Protein 320 acts as a transcription factor. This protein with a molecular mass of roughly 77 kDa shows expression especially in the nucleus of cells. It belongs to the zinc finger protein family known for their involvement in DNA binding and gene regulation. Understanding its expression pattern researchers identify it in various tissues but often focus on its higher levels in the brain and reproductive tissues.

Biological function summary

ZNF320 plays a role in the regulation of gene transcription. It does so by binding to specific DNA sequences influencing the transcription of particular genes. Although not a part of any large documented complex it interacts with other proteins involved in transcriptional regulation. These interactions suggest its contribution to controlling cellular processes such as cell cycle and differentiation.

Pathways

The regulation of gene expression heavily involves ZNF320. It functions within pathways related to transcriptional regulation and cellular differentiation. For example it interacts with pathways that include the transcription factor Sp1. Sp1 is another zinc finger protein known for regulating genes involved with cell growth and apoptosis. These interactions suggest ZNF320's role in controlling cellular responses and maintaining homeostasis.

Researchers have explored ZNF320's link to cancer and neurodegenerative disorders. Elevated levels of ZNF320 connect with processes that could lead to tumorigenesis making it an area of interest in cancer study. Moreover in the context of neurodegenerative diseases its interaction with proteins involved in cell survival pathways draws attention. The protein's regulatory influence might affect cellular responses to stress offering potential insights into therapeutic targets.