Recombinant Human ZNF358 protein is a Human Full Length protein, in the 1 to 481 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Images
Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
Amino acid sequence
M S S S F D L D P D V I G P V P L I L D P N S D T L S P G D P K V D P I S S G L T A T P Q V L A T S P A V L P A P A S P P R P F S C P D C G R A F R R S S G L S Q H R R T H S G E K P Y R C P D C G K S F S H G A T L A Q H R G I H T G A R P Y Q C A A C G K A F G W R S T L L K H R S S H S G E K P H H C P V C G K A F G H G S L L A Q H L R T H G G P R P H K C P V C A K G F G Q G S A L L K H L R T H T G E R P Y P C P Q C G K A F G Q S S A L L Q H Q R T H T A E R P Y R C P H C G K A F G Q S S N L Q H H L R I H T G E R P Y A C P H C S K A F G Q S S A L L Q H L H V H S G E R P Y R C Q L C G K A F G Q A S S L T K H K R V H E G A A A A A A A A A A A A A A A A A G L G L G P G L S P A S M M R P G Q V S L L G P D A V S V L G S G L G L S P G T S S G R N P D P G S G P G T L P D P S S K P L P G S R S T P S P T P V E S S D P K A G H D A G P D L V P S P D L D P V P S P D P D P V P S P D P N P V S C P D P C S P T R G T V S P A L P T G E S P E W V Q E Q G A L L G P D G
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Alternative names
Zinc finger protein 358, ZNF358
Recommended products
Recombinant Human ZNF358 protein is a Human Full Length protein, in the 1 to 481 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
- Accession
- Q9NW07-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
- M S S S F D L D P D V I G P V P L I L D P N S D T L S P G D P K V D P I S S G L T A T P Q V L A T S P A V L P A P A S P P R P F S C P D C G R A F R R S S G L S Q H R R T H S G E K P Y R C P D C G K S F S H G A T L A Q H R G I H T G A R P Y Q C A A C G K A F G W R S T L L K H R S S H S G E K P H H C P V C G K A F G H G S L L A Q H L R T H G G P R P H K C P V C A K G F G Q G S A L L K H L R T H T G E R P Y P C P Q C G K A F G Q S S A L L Q H Q R T H T A E R P Y R C P H C G K A F G Q S S N L Q H H L R I H T G E R P Y A C P H C S K A F G Q S S A L L Q H L H V H S G E R P Y R C Q L C G K A F G Q A S S L T K H K R V H E G A A A A A A A A A A A A A A A A A G L G L G P G L S P A S M M R P G Q V S L L G P D A V S V L G S G L G L S P G T S S G R N P D P G S G P G T L P D P S S K P L P G S R S T P S P T P V E S S D P K A G H D A G P D L V P S P D L D P V P S P D P D P V P S P D P N P V S C P D P C S P T R G T V S P A L P T G E S P E W V Q E Q G A L L G P D G
- Accession
- Q9NW07
- Protein length
- Full Length
- Amino acids
- 1 to 481
- Nature
- Recombinant
- Tags
- GST tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
May be involved in transcriptional regulation.
- Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
- Subcellular localisation
- Nucleus
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
ZNF358 also known as ZFP358 is a zinc finger protein playing a role in gene transcription regulation. It has a molecular mass of approximately 85 kDa. This protein is known to bind DNA in a sequence-specific manner using the zinc finger motifs to function as a transcription factor. ZNF358 expression occurs in multiple tissues with research indicating significant levels in the brain and heart. The protein's mechanical action involves modulating the transcription of specific genes impacting various biological processes.
- Biological function summary
ZNF358 modulates critical processes in cellular differentiation and development. As a member of the transcription factor family ZNF358 does not form part of a known multi-protein complex. Instead it functions independently influencing the transcription of genes involved in cellular responses and structural development. This protein plays a role in maintaining cellular homeostasis affecting developmental stages by activating or repressing target gene transcription.
- Pathways
ZNF358 influences several notably the Wnt signaling pathway and the Notch signaling pathway. In the Wnt signaling pathway ZNF358 interacts with proteins involved in cellular growth and differentiation such as β-catenin. This pathway plays a significant role in embryonic development and tissue regeneration. In relation to Notch signaling ZNF358 interacts with pathway components influencing cell fate determination and neural development collaborating with proteins like Notch receptors.
- Associated diseases and disorders
ZNF358 shows associations with developmental disorders particularly related to neural and cardiac malformations. Aberrant expression or dysfunction of ZNF358 may contribute to conditions like congenital heart defects due to its impact on cardiac development genes. Additionally disrupted ZNF358 function has links to neurodevelopmental disorders influencing neural pathway genes. Any interactions leading to disease often involve other transcription factors that interact with this protein in the developmental pathways.
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1 product image
SDS-PAGE - Recombinant Human ZNF358 protein (ab165455)
ab165455 on a 12.5% SDS-PAGE stained with Coomassie Blue.
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Product protocols
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