Recombinant Human ZNF417 protein (His-DHFR tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF417 also known as Zinc Finger Protein 417 is a transcription factor that belongs to the large family of zinc finger proteins which play a role in DNA-binding and gene regulation. The protein has a molecular mass of approximately 58 kDa. Researchers have observed the expression of ZNF417 in various tissues including the brain liver and kidney indicating its involvement in multiple physiological processes. By binding to DNA ZNF417 might influence the transcription of specific genes contributing to the regulation of important genetic networks.

Biological function summary

This transcription factor is implicated in modulating gene expression by interacting with other components of gene regulatory complexes. It may participate as part of larger protein complexes that control transcriptional activity and influence cellular responses. Through these interactions ZNF417 aids in the maintenance of proper cell function development and differentiation. Its DNA-binding ability highlights its role in fine-tuning the expression of target genes necessary for cellular homeostasis.

Pathways

Scientists recognize ZNF417's involvement in genetic regulatory networks related to cell cycle control and signal transduction. It associates with other proteins in pathways such as the p53 signaling pathway which is important for cell growth regulation and apoptosis. ZNF417 may work alongside proteins like MDM2 and TP53 to ensure the proper response to cellular stress contributing to the maintenance of genomic stability and prevention of uncontrolled cell proliferation.

Studies suggest that ZNF417 might relate to certain types of cancer given its involvement in gene regulation and cell cycle pathways. Changes in ZNF417 expression or function can affect cellular proliferation and may be connected to the development of tumorigenic states. Additionally ZNF417 has potential links to neurological disorders possibly due to its expression in the brain and its role in regulating genes required for neural function. Further understanding of ZNF417's associations with proteins like TP53 might provide insights into therapeutic approaches for these diseases.