Recombinant Human ZNF514 protein (denatured) is a Human Full Length protein, in the 1 to 400 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
Images
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S M T F E D V A V E F S Q W E W G Q L N P A Q K D L Y R E V M L E N F R N L A I L G L L V S K P Y V I C Q L E E G G E P F M V E R E I S T G A H S D W K R R S K S K E S M P S W G I S K E E L F Q V V S V E K H I Q D V L Q F S K L K A A C G C D G Q L E M Q Q I K Q E R H L K Q M S T I H K S A T T L S R D Y K W N G F G R S L G L R S V L V N Q H S I L M G E G S Y K C D T E F R Q T L G G N N S Q R T H P E K K S C K C N E C G K S F H F Q S E L R R H Q R C H T G E K P Y E C S D C G R A F G H I S S L I K H Q R T H T G E K P Y E C S E C G R A F S Q S S S L V L H Y R F H T G E K P Y K C N E C G R A F G H T S S L I K H Q R T H T G E K P Y E C R E C G R T F S Q S S S L I V H Y R F H T G E K P Y K C N K C G R A F S Q S S S L T Q H Y R F H T G E K P Y K C N E C G R A F A H T A S L I K H Q R S H A G K K T L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Alternative names
Zinc finger protein 514, ZNF514
Recommended products
Recombinant Human ZNF514 protein (denatured) is a Human Full Length protein, in the 1 to 400 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q96K75-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris-HCl buffer
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S M T F E D V A V E F S Q W E W G Q L N P A Q K D L Y R E V M L E N F R N L A I L G L L V S K P Y V I C Q L E E G G E P F M V E R E I S T G A H S D W K R R S K S K E S M P S W G I S K E E L F Q V V S V E K H I Q D V L Q F S K L K A A C G C D G Q L E M Q Q I K Q E R H L K Q M S T I H K S A T T L S R D Y K W N G F G R S L G L R S V L V N Q H S I L M G E G S Y K C D T E F R Q T L G G N N S Q R T H P E K K S C K C N E C G K S F H F Q S E L R R H Q R C H T G E K P Y E C S D C G R A F G H I S S L I K H Q R T H T G E K P Y E C S E C G R A F S Q S S S L V L H Y R F H T G E K P Y K C N E C G R A F G H T S S L I K H Q R T H T G E K P Y E C R E C G R T F S Q S S S L I V H Y R F H T G E K P Y K C N K C G R A F S Q S S S L T Q H Y R F H T G E K P Y K C N E C G R A F A H T A S L I K H Q R S H A G K K T L
- Accession
- Q96K75
- Protein length
- Full Length
- Predicted molecular weight
- 48.3 kDa
- Amino acids
- 1 to 400
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab171495 was purified using anion-exchange chromatography and gel-filtration chromatography with 20mM Tris pH 7.5, 2mM EDTA.
General info
- Function
May be involved in transcriptional regulation.
- Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
- Subcellular localisation
- Nucleus
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
ZNF514 also known as Zinc Finger Protein 514 is a protein belonging to the zinc finger family. It functions as a transcription factor involved in the regulation of gene expression. ZNF514 weighs approximately 82 kDa and contains several zinc finger motifs which are critical for binding to DNA. This protein is expressed mainly in the testis and at lower levels in several other tissues.
- Biological function summary
Zinc finger-containing proteins like ZNF514 play roles in DNA recognition and RNA packaging. As a transcription factor ZNF514 may regulate a set of target genes by binding to specific DNA sequences. It does not appear to be part of any known large protein complex but interacts with other transcriptional regulators to modulate gene expression. Researchers continue to explore the exact biological roles of ZNF514 in cellular processes and development.
- Pathways
ZNF514 interacts in gene regulatory networks and not directly into well-characterized pathways such as MAPK or PI3K/Akt. Still its activity influences downstream effects due to regulation of genes involved in cell proliferation and differentiation. Researchers are interested in understanding how ZNF514 collaborates with other key transcription factors or signaling proteins to affect these biological pathways.
- Associated diseases and disorders
Scientists are investigating ZNF514 for potential links to reproductive health issues owing to its expression in the testis and possible role in spermatogenesis. Moreover aberrations in genes encoding zinc finger proteins including ZNF514 have been studied in relation to certain cancers. Research is examining if ZNF514 interacts with other zinc finger proteins like ZNF217 frequently associated with oncogenic processes to contribute to tumorigenesis.
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1 product image
SDS-PAGE - Recombinant Human ZNF514 protein (denatured) (ab171495)
15% SDS-PAGE analysis of ab171495 (3µg).
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