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AB171495

Recombinant Human ZNF514 protein (denatured)

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Recombinant Human ZNF514 protein (denatured) is a Human Full Length protein, in the 1 to 400 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

View Alternative Names

Zinc finger protein 514, ZNF514

1 Images
SDS-PAGE - Recombinant Human ZNF514 protein (denatured) (AB171495)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ZNF514 protein (denatured) (AB171495)

15% SDS-PAGE analysis of ab171495 (3µg).

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q96K75

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris-HCl buffer

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMTFEDVAVEFSQWEWGQLNPAQKDLYREVMLENFRNLAILGLLVSKPYVICQLEEGGEPFMVEREISTGAHSDWKRRSKSKESMPSWGISKEELFQVVSVEKHIQDVLQFSKLKAACGCDGQLEMQQIKQERHLKQMSTIHKSATTLSRDYKWNGFGRSLGLRSVLVNQHSILMGEGSYKCDTEFRQTLGGNNSQRTHPEKKSCKCNECGKSFHFQSELRRHQRCHTGEKPYECSDCGRAFGHISSLIKHQRTHTGEKPYECSECGRAFSQSSSLVLHYRFHTGEKPYKCNECGRAFGHTSSLIKHQRTHTGEKPYECRECGRTFSQSSSLIVHYRFHTGEKPYKCNKCGRAFSQSSSLTQHYRFHTGEKPYKCNECGRAFAHTASLIKHQRSHAGKKTL","proteinLength":"Full Length","predictedMolecularWeight":"48.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":400,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96K75","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF514 also known as Zinc Finger Protein 514 is a protein belonging to the zinc finger family. It functions as a transcription factor involved in the regulation of gene expression. ZNF514 weighs approximately 82 kDa and contains several zinc finger motifs which are critical for binding to DNA. This protein is expressed mainly in the testis and at lower levels in several other tissues.
Biological function summary

Zinc finger-containing proteins like ZNF514 play roles in DNA recognition and RNA packaging. As a transcription factor ZNF514 may regulate a set of target genes by binding to specific DNA sequences. It does not appear to be part of any known large protein complex but interacts with other transcriptional regulators to modulate gene expression. Researchers continue to explore the exact biological roles of ZNF514 in cellular processes and development.

Pathways

ZNF514 interacts in gene regulatory networks and not directly into well-characterized pathways such as MAPK or PI3K/Akt. Still its activity influences downstream effects due to regulation of genes involved in cell proliferation and differentiation. Researchers are interested in understanding how ZNF514 collaborates with other key transcription factors or signaling proteins to affect these biological pathways.

Scientists are investigating ZNF514 for potential links to reproductive health issues owing to its expression in the testis and possible role in spermatogenesis. Moreover aberrations in genes encoding zinc finger proteins including ZNF514 have been studied in relation to certain cancers. Research is examining if ZNF514 interacts with other zinc finger proteins like ZNF217 frequently associated with oncogenic processes to contribute to tumorigenesis.
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Specifications

Form

Liquid

Additional notes

ab171495 was purified using anion-exchange chromatography and gel-filtration chromatography with 20mM Tris pH 7.5, 2mM EDTA.

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General info

Function

May be involved in transcriptional regulation.

Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Subcellular localisation

Nucleus

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Product protocols

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Target data

May be involved in transcriptional regulation.
See full target information ZNF514
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