Recombinant Human ZNF518A protein (His-DHFR tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF518A also known as Zinc Finger Protein 518A is a protein that functions as a transcriptional regulator. It contains C2H2-type zinc finger domains which allow it to bind to specific DNA sequences and influence gene expression. The protein has a mass of approximately 87 kDa. ZNF518A shows expression in various tissues including the brain and testes indicating its potential role in diverse biological processes.

Biological function summary

ZNF518A participates in the regulation of gene expression within the cellular context. It acts as a part of transcriptional regulatory networks although it is not currently known to be part of a larger protein complex. Its expression and functional activity suggest it might influence developmental processes and cell differentiation potentially affecting how cells develop their specific roles within the organism.

Pathways

ZNF518A contributes to pathways involved in transcriptional regulation and signal transduction. In particular it links to the Notch signaling pathway a critical cascade in cell communication that manages cell fate decisions. ZNF518A potentially interacts with related transcription factors or pathways including the well-studied Myc protein family given their common involvement in regulating gene expression and cellular growth.

Abnormalities in ZNF518A have connections to certain cancers and neurological conditions. Research suggests it might play a role in tumor progression possibly through its interactions with proteins like p53 which is important in controlling cell division and apoptosis. In neurological contexts its altered expression could relate to disorders such as autism spectrum disorder (ASD) where it might link to other transcriptional regulators influencing neural development.