Recombinant Human ZNF562 protein

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF562 also known as Zinc Finger Protein 562 functions as a transcription factor which regulates gene expression by binding to DNA sequences. This protein has a mass of approximately 74 kDa. Scientists have detected ZNF562 in various body tissues but it shows higher levels of expression in the liver and testis. The zinc finger motifs in ZNF562 interact with specific DNA sequences which guide the transcriptional activity of certain genes.

Biological function summary

The regulation of gene expression by ZNF562 influences cell differentiation and development. ZNF562 is part of the large family of zinc finger proteins involved in transcriptional regulation. These proteins usually form parts of larger protein complexes that coordinate the transcription process. The activity of ZNF562 can determine the fate of cell types by influencing which genes are turned on or off during differentiation.

Pathways

ZNF562 participates in transcriptional regulation pathways and is important in orchestrating gene networks that define cellular functions. Specifically it interacts with other transcription factors like SP1 and EGR1 within these pathways to modulate gene expression. ZNF562 plays an essential part in the crosstalk between different regulatory proteins helping maintain the balance of gene activity in response to cellular signals.

Alterations in ZNF562 expression have associations with certain cancers and liver diseases. Changes in the regulation or mutation of ZNF562 might disrupt normal cell growth leading to oncogenesis. Researchers have noted that ZNF562 may interact with tumor suppressor proteins like p53 in cancer contexts. Additionally abnormal expression of ZNF562 could contribute to liver dysfunction by altering transcriptional profiles within the liver indicating a potential role in liver disease pathogenesis.