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AB152072

Recombinant Human ZNF75A protein

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Recombinant Human ZNF75A protein is a Human Fragment protein, in the 58 to 162 aa range, expressed in Escherichia coli, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Zinc finger protein 75A, ZNF75A

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q96N20

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in PBS

Storage buffer

pH: 7.4 Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"SPEFKDSAGKSPTGLKLKNDTENHQPVSLSDLEIQASAGVISKKAKVKVPQKTAGKENHFDMHRVGKWHQDFPVKKRKKLSTWKQELLKLMDRHKKDCAREKPFK","proteinLength":"Fragment","predictedMolecularWeight":"12.03 kDa","actualMolecularWeight":null,"aminoAcidEnd":162,"aminoAcidStart":58,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96N20","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
A few weeks
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ZNF75A also known as Zinc Finger Protein 75A is a type of zinc finger protein with a molecular mass of approximately 39 kDa. This protein functions as a transcription factor which means it binds to DNA and influences gene expression. ZNF75A contains several zinc finger motifs which are small protein structural motifs that stabilize its interaction with DNA. The protein is widely expressed in various tissues including the brain and liver suggesting its involvement in multiple biological processes.
Biological function summary

ZNF75A acts as a regulator of gene transcription controlling the expression of specific genes. It does not appear to be part of a larger protein complex but interacts with DNA directly to modulate gene activity. As a transcription factor ZNF75A plays roles in cell growth differentiation and apoptosis which are critical for maintaining cellular homeostasis. Its activity in diverse tissues highlights its potential regulatory role in various biological contexts.

Pathways

ZNF75A integrates into transcriptional regulation pathways that include vital proteins such as RNA polymerase II. It can influence the Wnt signaling pathway which impacts cell fate decisions and embryonic development. ZNF75A may also interact with other transcription factors and signaling molecules within these pathways coordinating responses that affect cell behavior and phenotype.

ZNF75A is linked to conditions like cancer where abnormal regulation of transcription factors can lead to uncontrolled cell proliferation. For example dysregulated expression of ZNF75A might interact with oncogenic proteins contributing to tumor development or progression. Additionally disorders affecting brain function could involve ZNF75A as altered transcription activity can impact neurological gene expression. ZNF75A may interact with neurodegenerative proteins playing a role in the pathology of these diseases.
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Specifications

Form

Lyophilized

Additional notes

ab152072 is lyophilized from an 0.2 µM filtered solution.

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General info

Function

May be involved in transcriptional regulation.

Sequence similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Subcellular localisation

Nucleus

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in transcriptional regulation.
See full target information ZNF75A
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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