Recombinant Influenza A Virus Hemagglutinin H3 protein (His tag) is a Influenza A virus (A/Hong Kong/1/1968(H3N2)) Fragment protein, in the 17 to 529 aa range, expressed in HEK 293, with >95% purity and suitable for SDS-PAGE.
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Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
Q D L P G N D N S T A T L C L G H H A V P N G T L V K T I T D D Q I E V T N A T E L V Q S S S T G K I C N N P H R I L D G I D C T L I D A L L G D P H C D V F Q N E T W D L F V E R S K A F S N C Y P Y D V P D Y A S L R S L V A S S G T L E F I T E G F T W T G V T Q N G G S N A C K R G P G S G F F S R L N W L T K S G S T Y P V L N V T M P N N D N F D K L Y I W G V H H P S T N Q E Q T S L Y V Q A S G R V T V S T R R S Q Q T I I P N I G S R P W V R G L S S R I S I Y W T I V K P G D V L V I N S N G N L I A P R G Y F K M R T G K S S I M R S D A P I D T C I S E C I T P N G S I P N D K P F Q N V N K I T Y G A C P K Y V K Q N T L K L A T G M R N V P E K Q T R G L F G A I A G F I E N G W E G M I D G W Y G F R H Q N S E G T G Q A A D L K S T Q A A I D Q I N G K L N R V I E K T N E K F H Q I E K E F S E V E G R I Q D L E K Y V E D T K I D L W S Y N A E L L V A L E N Q H T I D L T D S E M N K L F E K T R R Q L R E N A E D M G N G C F K I Y H K C D N A C I E S I R N G T Y D H D V Y R D E A L N N R F Q I K G V E L K S G Y K D
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Target data
Function
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Additional Targets
Influenza A Virus Hemagglutinin H3
Alternative names
Hemagglutinin, HA
Recommended products
Recombinant Influenza A Virus Hemagglutinin H3 protein (His tag) is a Influenza A virus (A/Hong Kong/1/1968(H3N2)) Fragment protein, in the 17 to 529 aa range, expressed in HEK 293, with >95% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- HEK 293 cells
- Tags
- His tag C-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q91MA7-1
- Animal free
- No
- Species
- Influenza A virus (A/Hong Kong/1/1968(H3N2))
- Concentration
- Storage buffer
Constituents: 100% PBS
Sequence info
Amino acid sequence
- Q D L P G N D N S T A T L C L G H H A V P N G T L V K T I T D D Q I E V T N A T E L V Q S S S T G K I C N N P H R I L D G I D C T L I D A L L G D P H C D V F Q N E T W D L F V E R S K A F S N C Y P Y D V P D Y A S L R S L V A S S G T L E F I T E G F T W T G V T Q N G G S N A C K R G P G S G F F S R L N W L T K S G S T Y P V L N V T M P N N D N F D K L Y I W G V H H P S T N Q E Q T S L Y V Q A S G R V T V S T R R S Q Q T I I P N I G S R P W V R G L S S R I S I Y W T I V K P G D V L V I N S N G N L I A P R G Y F K M R T G K S S I M R S D A P I D T C I S E C I T P N G S I P N D K P F Q N V N K I T Y G A C P K Y V K Q N T L K L A T G M R N V P E K Q T R G L F G A I A G F I E N G W E G M I D G W Y G F R H Q N S E G T G Q A A D L K S T Q A A I D Q I N G K L N R V I E K T N E K F H Q I E K E F S E V E G R I Q D L E K Y V E D T K I D L W S Y N A E L L V A L E N Q H T I D L T D S E M N K L F E K T R R Q L R E N A E D M G N G C F K I Y H K C D N A C I E S I R N G T Y D H D V Y R D E A L N N R F Q I K G V E L K S G Y K D
- Protein length
- Fragment
- Amino acids
- 17 to 529
- Nature
- Recombinant
- Tags
- His tag C-Terminus
Specifications
- Form
- Liquid
General info
- Function
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
- Sequence similarities
Belongs to the influenza viruses hemagglutinin family.
- Post-translational modifications
Palmitoylated.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- Up to 12 months
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
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SDS-PAGE - Recombinant Influenza A Virus Hemagglutinin H3 protein (His tag) (ab217642)
SDS-PAGE - Recombinant Influenza A Virus Hemagglutinin H3 protein (His tag) (ab217642)
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