Recombinant Mouse Calreticulin protein (His tag)
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Recombinant Mouse Calreticulin protein (His tag) is a Mouse Full Length protein, in the 18 to 416 aa range, expressed in Yeast, with >90%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, ERp60, Calr
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of ab240775 could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calreticulin.
- Mass Spec
Supplier Data
Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of ab240775 could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calreticulin.
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab240775.
Reactivity data
Sequence info
Properties and storage information
Form
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
General info
Function
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 20880849, PubMed : 21652723). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
Sequence similarities
Belongs to the calreticulin family.
Subcellular localisation
Cytolytic granule
Target data
Product promise
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