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AB240775

Recombinant Mouse Calreticulin protein (His tag)

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Recombinant Mouse Calreticulin protein (His tag) is a Mouse Full Length protein, in the 18 to 416 aa range, expressed in Yeast, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, ERp60, Calr

3 Images
Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of ab240775 could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calreticulin.

Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Mouse Calreticulin protein (His tag) (AB240775)

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of ab240775 could indicate that this peptide derived from Yeast-expressed Mus musculus (Mouse) Calreticulin.

SDS-PAGE - Recombinant Mouse Calreticulin protein (His tag) (AB240775)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Mouse Calreticulin protein (His tag) (AB240775)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel analysis of ab240775.

Key facts

Purity

>90% SDS-PAGE

Expression system

Yeast

Tags

6x His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

P14211

Animal free

No

Carrier free

No

Species

Mouse

Storage buffer

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"linker":null,"sequence":"DPAIYFKEQFLDGDAWTNRWVESKHKSDFGKFVLSSGKFYGDLEKDKGLQTSQDARFYALSAKFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPSGLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDDDRDEDEDEEDEKEEDEEESPGQAKDEL","proteinLength":"Full Length","predictedMolecularWeight":"48.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":416,"aminoAcidStart":18,"nature":"Recombinant","expressionSystem":"Yeast","accessionNumber":"P14211","tags":[{"tag":"6x His","terminus":"N-Terminus"}]}]

Properties and storage information

Form
Liquid
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False

General info

Function

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 20880849, PubMed : 21652723). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).

Sequence similarities

Belongs to the calreticulin family.

Subcellular localisation

Cytolytic granule

Product protocols

Target data

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 20880849, PubMed : 21652723). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
See full target information Calr

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