Recombinant Mouse Cardiac Troponin I protein (His tag)
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Recombinant Mouse Cardiac Troponin I protein (His tag) is a Mouse Full Length protein, in the 2 to 211 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
View Alternative Names
Cardiac troponin I, Tnni3
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse Cardiac Troponin I protein (His tag) (AB226425)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab226425 with 5% enrichment gel and 15% separation gel.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Sequence similarities
Belongs to the troponin I family.
Post-translational modifications
Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-32. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T) (By similarity). Phosphorylated at Ser-43 and Ser-45 by PRKCE; phosphorylation increases myocardium contractile dysfunction.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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