Recombinant Mouse Fc epsilon RI/FCER1A protein (Tagged)
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Recombinant Mouse Fc epsilon RI/FCER1A protein (Tagged) is a Mouse Full Length protein, in the 24 to 250 aa range, expressed in Cell free, with >90%, suitable for SDS-PAGE.
View Alternative Names
Fce1a, Fcer1a, High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Mouse Fc epsilon RI/FCER1A protein (Tagged) (AB235018)
ab235018 analyzed by (Tris-Glycine gel) discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Specifications
Form
Liquid
General info
Function
High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
Target data
Product promise
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